Background Ethnic differences have the potential to confound associations between HIV-1
subtype and immunologic progression. We compared declines in CD4 cell counts during …

Objective: We investigated the effect of descent (African versus European) on the
progression of untreated HIV infections in a prospective cohort study of HIV-1-infected …

Background Our intention was to compare the rate of immunological progression prior to
antiretroviral therapy (ART) and the virological response to ART in patients infected with …

Background Patients accessing antiretroviral treatment (ART) programmes in sub-Saharan
Africa frequently have very advanced immunodeficiency. Previous data suggest that such …

Objectives Recent studies have reported faster progression of HIV infection than anticipated
based on results from earlier studies. The aim of the present study was to examine if the …

Background CD4 count is a proxy for the extent of immune deficiency and declines in CD4
count are a measure of disease progression. Decline in CD4 count is an important …

Background. The extent to which immunologic and clinical biomarkers influence human
immunodeficiency virus type 1 (HIV-1) infection outcomes remains incompletely …

Summary Objective To assess whether African ethnicity is independently associated with a
poorer CD4 reconstitution with highly active antiretroviral therapy (HAART) compared to …

Objective: The influence of viral subtype on the natural history of HIV is unclear and
confounded by socioeconomic and host factors that vary between groups harboring different …

Background: Even among HIV-infected patients who fully suppress plasma HIV RNA
replication on antiretroviral therapy, genetic (eg CCL3L1 copy number), viral (eg tropism) …