Transforming the care of patients with diabetic kidney disease

FC Brosius, D Cherney, PO Gee… - Clinical Journal of the …, 2021 - journals.lww.com
Diabetes and its associated complications pose an immediate threat to humankind. Diabetic
kidney disease is one of the most devastating complications, increasing the risk of death …

Use of sodium–glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study

C Iskander, DZ Cherney, KK Clemens, SN Dixon… - Cmaj, 2020 - Can Med Assoc
BACKGROUND: Regulatory agencies warn about the risk of acute kidney injury (AKI) after
the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to …

[HTML][HTML] Platelet count and survival after cancer

V Giannakeas, J Kotsopoulos, JD Brooks, MC Cheung… - Cancers, 2022 - mdpi.com
Simple Summary Platelets are cellular fragments circulating in the blood that are
responsible for clotting. Previous research has shown that cancer patients with an …

[HTML][HTML] Incidence, predictors and patterns of care of patients with very severe hypertriglyceridemia in Ontario, Canada: a population-based cohort study

AJ Berberich, AM Ouédraogo, SZ Shariff… - Lipids in Health and …, 2021 - Springer
Background The incidence of severe (S-HTG) and very severe hypertriglyceridemia (VS-
HTG) among Canadians is unknown. This study aimed to determine the incidence …

The risk of acute kidney injury with oral anticoagulants in elderly adults with atrial fibrillation

Z Harel, E McArthur, N Jeyakumar… - Clinical Journal of the …, 2021 - journals.lww.com
Results Each direct oral anticoagulant was associated with a significantly lower risk of AKI
compared with warfarin (weighted hazard ratio, 0.65; 95% confidence interval, 0.53 to 0.80 …

Rural–urban differences in suicide mortality: an observational study in Newfoundland and Labrador, Canada: Différences de la Mortalité par suicide en milieu rural …

C Reccord, N Power, K Hatfield… - The Canadian …, 2021 - journals.sagepub.com
Contexte: Les taux de suicide sont plus élevés en milieu rural qu'en milieu urbain. Bien que
ce modèle semble être alimenté par des taux plus élevés chez les hommes, les données …

[HTML][HTML] An interactive geographic information system to inform optimal locations for healthcare services

C Nicholson, M Hanly, DS Celermajer - PLOS digital health, 2023 - journals.plos.org
Large health datasets can provide evidence for the equitable allocation of healthcare
resources and access to care. Geographic information systems (GIS) can help to present this …

Hyponatremia‐associated hospital visits are not reduced by early electrolyte testing in older adults starting antidepressants

NE Lane, L Bai, DP Seitz, DN Juurlink… - Journal of the …, 2024 - Wiley Online Library
Background Clinical practice guidelines recommend early serum electrolyte monitoring
when starting antidepressants in older adults due to the increased risk of hyponatremia. It is …

[HTML][HTML] Diabetes after pregnancy: a study protocol for the derivation and validation of a risk prediction model for 5-year risk of diabetes following pregnancy

SH Read, LC Rosella, H Berger, DS Feig… - Diagnostic and …, 2021 - Springer
Background Pregnancy offers a unique opportunity to identify women at higher future risk of
type 2 diabetes mellitus (DM). In pregnancy, a woman has greater engagement with the …

Hypocalcemia Risk of Denosumab Across the Spectrum of Kidney Disease: A Population‐Based Cohort Study

A Cowan, N Jeyakumar, E McArthur… - Journal of Bone and …, 2020 - academic.oup.com
Denosumab can be used in patients with chronic kidney disease (CKD) but has been linked
with cases of severe hypocalcemia. The incidence of and risk factors for hypocalcemia after …