The deepening opioid crisis in North America: historical context and current solutions

JH Donroe, ME Socias, BDL Marshall - Current Addiction Reports, 2018 - Springer
Abstract Purpose of Review The purpose of this review is to (1) detail the historical context
behind the rise of opioid use disorder (OUD) and opioid-related harms in the United States …

Contributions of prescribed and non-prescribed opioids to opioid related deaths: population based cohort study in Ontario, Canada

T Gomes, W Khuu, D Martins, M Tadrous, MM Mamdani… - bmj, 2018 - bmj.com
Objective To describe the contributions of prescribed and non-prescribed opioids to opioid
related deaths. Design Population based cohort study. Setting Ontario, Canada, from 1 …

[HTML][HTML] Permissive regulation: A critical review of the regulatory history of buprenorphine formulations in Canada

A Sud, M McGee, B Mintzes, M Herder - International Journal of Drug …, 2022 - Elsevier
Suboxone (buprenorphine-naloxone) is an opioid product approved in the US and Canada
for the treatment of opioid use disorder. The drug is considered an important response to the …

Shifts in substance use patterns among a cohort of people who use opioids after delisting of OxyContin in BC, Canada: An interrupted time series study

M Karamouzian, JA Buxton, C Hategeka… - International Journal of …, 2022 - Elsevier
Background OxyContin was delisted from Canadian provincial drug formularies in March
2012 and replaced with a reformulated tamper-resistant form of oxycodone (ie, OxyNeo). We …

[PDF][PDF] Understanding the implications of a shifting opioid landscape in Ontario

T Gomes, DN Juurlink - Healthc Q, 2019 - researchgate.net
North America is currently in the midst of an opioid overdose crisis, leading to changes in
drug policy and clinical practice guideline recommendations. Data from Ontario's …

Endogenous opiates and behavior: 2017

RJ Bodnar - Peptides, 2020 - Elsevier
This paper is the fortieth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Time trends in opioid prescribing among Ontario long-term care residents: a repeated cross-sectional study

A Iaboni, MA Campitelli, SE Bronskill… - … Open Access Journal, 2019 - cmajopen.ca
Background: Opioids are an important pain therapy, but their use may be associated with
adverse events in frail and cognitively impaired long-term care residents. The objective of …

[HTML][HTML] Trends in postoperative opioid prescribing in Ontario between 2013 and 2019: a population-based cohort study

NK Jivraj, K Ladha, A Goel, A Hill… - Canadian Journal of …, 2022 - Springer
Purpose Many hospital and provincial-level recommendations now advise a tailored
approach to postoperative opioid prescribing; recent trends in postoperative prescribing at …

Trends in postpartum opioid prescribing: a time series analysis

JS Zipursky, A Pang, JM Paterson… - Clinical …, 2021 - Wiley Online Library
Opioids are commonly prescribed following childbirth, but data are lacking on trends in
postpartum opioid prescribing over time. We examined whether a highly publicized 2006 …

[HTML][HTML] “And this is the life jacket, the lifeline they've been wanting”: Participant perspectives on navigating challenges and successes of prescribed safer supply

N Henderson, J Marris, K Woodend - PloS one, 2024 - journals.plos.org
Background In 2021, 43% of drug toxicity deaths in Ontario were reported by public health
units serving medium-sized urban and rural communities. Safer supply programs (SSPs) …