Importance The literature is inconsistent regarding the impact of permanent pacemaker
implantation after transcatheter aortic valve replacement. Objective To evaluate clinical and …

Background Depression is strongly linked to increased morbidity and mortality in patients
with chronic stable angina; however, its associated healthcare costs have been less well …

Background Colchicine is an anti-inflammatory therapy with a low associated cost that has
been shown in 2 large studies to reduce cardiovascular (CV) events, but its use is …

Background Cardiovascular (CV) disease is a condition with high levels of morbidity and
mortality. Canakinumab is a novel monoclonal antibody therapy that has been shown to …

In Ontario, individuals who have experienced a cardiac event are prescribed to participate in
cardiac rehabilitation. Most research examining the effectiveness of cardiac rehabilitation …