User profiles for Tina Hu

Tina Hu-Seliger

Elysium Health
Verified email at elysiumhealth.com
Cited by 8196

Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines

…, M Horton, Y Li, D Meng, A Platt, AM Tarone, TT Hu… - Nature, 2010 - nature.com
Although pioneered by human geneticists as a potential solution to the challenging problem
of finding the genetic basis of common human diseases 1 , 2 , genome-wide association (…

[HTML][HTML] The Pattern of Polymorphism in Arabidopsis thaliana

M Nordborg, TT Hu, Y Ishino, J Jhaveri… - PLoS …, 2005 - journals.plos.org
We resequenced 876 short fragments in a sample of 96 individuals of Arabidopsis thaliana
that included stock center accessions as well as a hierarchical sample from natural …

The Arabidopsis lyrata genome sequence and the basis of rapid genome size change

TT Hu, P Pattyn, EG Bakker, J Cao, JF Cheng… - Nature …, 2011 - nature.com
We report the 207-Mb genome sequence of the North American Arabidopsis lyrata strain MN47
based on 8.3× dideoxy sequence coverage. We predict 32,670 genes in this outcrossing …

Common Sequence Polymorphisms Shaping Genetic Diversity in Arabidopsis thaliana

…, S Ossowski, G Zeller, P Shinn, N Warthmann, TT Hu… - science, 2007 - science.org
The genomes of individuals from the same species vary in sequence as a result of different
evolutionary processes. To examine the patterns of, and the forces shaping, sequence …

Recombination and linkage disequilibrium in Arabidopsis thaliana

S Kim, V Plagnol, TT Hu, C Toomajian, RM Clark… - Nature …, 2007 - nature.com
Linkage disequilibrium (LD) is a major aspect of the organization of genetic variation in
natural populations. Here we describe the genome-wide pattern of LD in a sample of 19 …

Population resequencing reveals local adaptation of Arabidopsis lyrata to serpentine soils

TL Turner, EC Bourne, EJ Von Wettberg, TT Hu… - Nature …, 2010 - nature.com
A powerful way to map functional genomic variation and reveal the genetic basis of local
adaptation is to associate allele frequency across the genome with environmental conditions 1 , …

Multiplexed shotgun genotyping for rapid and efficient genetic mapping

P Andolfatto, D Davison, D Erezyilmaz, TT Hu… - Genome …, 2011 - genome.cshlp.org
We present a new approach to genotyping based on multiplexed shotgun sequencing that
can identify recombination breakpoints in a large number of individuals simultaneously at a …

[HTML][HTML] The Capsella rubella genome and the genomic consequences of rapid mating system evolution

…, S Takuno, Y Brandvain, G Coop, P Andolfatto, TT Hu… - Nature …, 2013 - nature.com
The shift from outcrossing to selfing is common in flowering plants 1 , 2 , but the genomic
consequences and the speed at which they emerge remain poorly understood. An excellent …

Natural allelic variation underlying a major fitness trade-off in Arabidopsis thaliana

M Todesco, S Balasubramanian, TT Hu, MB Traw… - Nature, 2010 - nature.com
Plants can defend themselves against a wide array of enemies, from microbes to large
animals, yet there is great variability in the effectiveness of such defences, both within and …

A second-generation assembly of the Drosophila simulans genome provides new insights into patterns of lineage-specific divergence

TT Hu, MB Eisen, KR Thornton, P Andolfatto - Genome research, 2013 - genome.cshlp.org
We create a new assembly of the Drosophila simulans genome using 142 million paired
short-read sequences and previously published data for strain w 501 . Our assembly represents …