The number of proposed prognostic models for coronavirus disease 2019 (COVID-19) is
growing rapidly, but it is unknown whether any are suitable for widespread clinical …

Background There is substantial variation in the reported treatment outcomes for adult
tuberculous meningitis (TBM). Data on survival and neurological disability by continent and HIV …

Introduction A highly sensitive triage test that captures most symptomatic patients at increased
likelihood of having pulmonary tuberculosis (PTB) would ‘rule-out’ lower-risk patients from …

Introduction Catastrophic costs incurred by tuberculosis (TB) patients have received considerable
attention, however little is known about costs and pathways to care after a negative TB …

BACKGROUND Dasatinib exhibited activity in preclinical models of sarcoma. The Sarcoma
Alliance for Research through Collaboration (SARC) conducted a multicenter, phase 2 trial …

… Megarity a , Thomas G. Roberts a , Thomas OM Samuels c , Martin Winkler b , Jamie H.
Warner ORCID logo c , Thomas Happe b and Fraser A. Armstrong ORCID logo * a …

Caenorhabditis elegans navigates thermal gradients by using a behavioral strategy that is
regulated by a memory of its cultivation temperature (T c ). At temperatures above or around …

In order to evaluate the impact of water deficit in field conditions, researchers or breeders must
set up large experiment networks in very restrictive field environments. Experience shows …

We present an extensive assessment of mutation burden through sequencing analysis of >81,000
tumors from pediatric and adult patients, including tumors with hypermutation caused …

Background Few treatment options exist for patients with severe central nervous system (CNS)
tuberculosis (TB) worsening due to inflammatory lesions, despite optimal antitubercular …