[HTML][HTML] Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an …
…, H Miah, S Kostrov, M Ramos, P Edwards, T Godec… - The Lancet, 2017 - thelancet.com
Background Post-partum haemorrhage is the leading cause of maternal death worldwide.
Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We …
Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We …
[HTML][HTML] Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial
…, H Santander, K Steinbrink, M Sticherling, C Thomas… - The Lancet, 2017 - thelancet.com
Background Bullous pemphigoid is a blistering skin disorder with increased mortality. We
tested whether a strategy of starting treatment with doxycycline gives acceptable short-term …
tested whether a strategy of starting treatment with doxycycline gives acceptable short-term …
Short-course treatment for multidrug-resistant tuberculosis: the STREAM trials
R Moodley, TR Godec - European Respiratory Review, 2016 - Eur Respiratory Soc
Multidrug-resistant (MDR) tuberculosis (TB) is a threat to global TB control, as suboptimal
and poorly tolerated treatment options have resulted in largely unfavourable outcomes for …
and poorly tolerated treatment options have resulted in largely unfavourable outcomes for …
Long-term mortality after blood pressure-lowering and lipid-lowering treatment in patients with hypertension in the Anglo-Scandinavian Cardiac Outcomes Trial …
A Gupta, J Mackay, A Whitehouse, T Godec, T Collier… - The Lancet, 2018 - thelancet.com
Background In patients with hypertension, the long-term cardiovascular and all-cause mortality
effects of different blood pressure-lowering regimens and lipid-lowering treatment are not …
effects of different blood pressure-lowering regimens and lipid-lowering treatment are not …
Patterns of glycaemic control in patients with type 2 diabetes mellitus initiating second‐line therapy after metformin monotherapy: R etrospective data for 10 256 …
K Khunti, TR Godec, J Medina… - Diabetes, Obesity …, 2018 - Wiley Online Library
Aim To investigate determinants of change in glycated haemoglobin (HbA1c) in patients
with type 2 diabetes mellitus (T2DM) at 6 months after initiating uninterrupted second‐line …
with type 2 diabetes mellitus (T2DM) at 6 months after initiating uninterrupted second‐line …
[HTML][HTML] Changes in HbA1c and weight, and treatment persistence, over the 18 months following initiation of second-line therapy in patients with type 2 diabetes …
Background Intensification of metformin monotherapy with additional glucose-lowering drugs
is often required in patients with type 2 diabetes (T2D). This study evaluated changes in …
is often required in patients with type 2 diabetes (T2D). This study evaluated changes in …
[HTML][HTML] Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis
Aims Increased cardiovascular disease risk underlies elevated rates of mortality in individuals
with periodontitis. A key characteristic of those with increased cardiovascular risk is …
with periodontitis. A key characteristic of those with increased cardiovascular risk is …
Computed tomography cardiac angiography before invasive coronary angiography in patients with previous bypass surgery: the BYPASS-CTCA trial
…, KS Rathod, M Andiapen, L Wynne, T Godec… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Patients with previous coronary artery bypass grafting often require invasive
coronary angiography (ICA). However, for these patients, the procedure is technically more …
coronary angiography (ICA). However, for these patients, the procedure is technically more …
Legacy benefits of blood pressure treatment on cardiovascular events are primarily mediated by improved blood pressure variability: the ASCOT trial
A Gupta, WN Whiteley, T Godec… - European Heart …, 2024 - academic.oup.com
Background and Aims Visit-to-visit systolic blood pressure variability (BPV) is an important
predictor of cardiovascular (CV) outcomes. The long-term effect of a period of blood pressure (…
predictor of cardiovascular (CV) outcomes. The long-term effect of a period of blood pressure (…
Longitudinal comparisons of mental health, burnout and well-being in patient-facing, non-patient-facing healthcare professionals and non-healthcare professionals …
Background The COVID-19 pandemic may disproportionately affect the mental health of
healthcare professionals (HCPs), especially patient-facing HCPs. Aims To longitudinally …
healthcare professionals (HCPs), especially patient-facing HCPs. Aims To longitudinally …