… refers to the positivity threshold (score greater than or equal to 1) used in this study. The
upper, light gray line refers to an alternative positivity threshold (score greater than or equal to 2) …

Appropriate use and interpretation of serological tests for assessments of SARS-CoV-2
exposure, infection and potential immunity require accurate assay performance data. We …

Pharmaceuticals have extensive reciprocal interactions with the microbiome, but whether
bacterial drug sensitivity and metabolism is driven by pathways conserved in host cells …

Despite the remarkable microbial diversity found within humans, our ability to link genes to
phenotypes is based upon a handful of model microorganisms. We report a comparative …

An obligately piezophilic strain was isolated from an amphipod crustacean obtained in the
Challenger Deep region of the Mariana Trench during the DEEPSEA CHALLENGE expedition…

… TT2012 was isolated from sediments rather than amphipods. … more basic proteins than their
piezosensitive counterparts. … also have more basic proteomes than free-living species [59], …

… Author links open overlay panel Than S. Kyaw 1 , Vaibhav Upadhyay 1 2 , Irina Tolstykh
3 , Katherine Van Loon 2 4 , Angela Laffan 4 , Dalila Stanfield 4 , Daryll Gempis 1 , Stacey A. …

Understanding interindividual variations in drug metabolism and disposition is critical to
reduce patient morbidity and mortality. The microbiome contributes to such variations in part …

Simple Summary The trillions of microorganisms found in the human gut have broad impacts
on health and disease including altering the risk of colorectal cancer. Given the emerging …

Drug efflux transporters are a major determinant of drug efficacy and toxicity. A canonical
example is P-glycoprotein (P-gp), an efflux transporter that controls the intestinal absorption of …