Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more
than one million deaths annually via development of cirrhosis, although no antifibrotic therapy …

… Takahiro Higashi received research support on an unrelated project from Pfizer Health …
Takahiro Higashi reviewed Japanese-language articles, drafted sections of the manuscript, and …

Background The potential for a global epidemic of asbestos-related diseases is a growing
concern. Our aim was to assess the ecological association between national death rates from …

… There were no significant differences in plasma cholesterol (147.39t 33.75 mg dl T"
compared with 14281 t 33.55 mg dl T" for MSRT" and MSR", respectively), triglyceride (245.38…

PURPOSE: To prospectively evaluate the elastographic appearance of thyroid gland tumors
and explore the potential sensitivity and specificity of ultrasonographic (US) elastography …

Prostaglandin E 2 (PGE 2 ) and prostaglandin I 2 (PGI 2 ) are major inflammatory mediators
that play important roles in pain sensation and hyperalgesia. The role of their receptors (EP …

… QW, T. Higashi, and T. Minegishi examined the compatibility of the water-splitting panel
with Z-scheme photocatalyst sheets and photoelectrodes. TY performed ICP-OES analyses. …

Long-term incubation of proteins with glucose leads to the formation of advanced glycation
end products (AGE). Recent immunological studies have suggested the potential role of AGE …

Proinflammatory agents trypsin and mast cell tryptase cleave and activate PAR2, which is
expressed on sensory nerves to cause neurogenic inflammation. Transient receptor potential …

There are eight thermosensitive TRP (transient receptor potential) channels in mammals, and
there might be other TRP channels sensitive to temperature stimuli. Here, we demonstrate …