High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis

S Mithoowani, K Gregory-Miller, J Goy… - The Lancet …, 2016 - thelancet.com
Background Whether high-dose dexamethasone has long-term efficacy and safety in
previously untreated patients with immune thrombocytopenia is unclear. We did a systematic …

[HTML][HTML] Investigation and management of erythrocytosis

S Mithoowani, M Laureano, MA Crowther, CM Hillis - Cmaj, 2020 - Can Med Assoc
We reviewed current guidelines on the management of polycythemia vera. For questions
regarding the diagnostic investigation of erythrocytosis and the utility of specific laboratory tests …

[HTML][HTML] First-line therapy for immune thrombocytopenia

S Mithoowani, DM Arnold - Hämostaseologie, 2019 - thieme-connect.com
Immune thrombocytopenia (ITP) is an autoimmune disease affecting blood platelets that
causes thrombocytopenia and an increased risk of bleeding. First-line therapy is indicated for …

[HTML][HTML] Direct oral anticoagulants after bariatric surgery—What is the evidence?

…, DK Chu, MA Crowther, S Mithoowani - Journal of Thrombosis and …, 2022 - Elsevier
Background Obesity is a global epidemic and bariatric surgery is used with increasing frequency
to treat its complications. The extent to which bariatric surgery alters the efficacy, safety, …

[HTML][HTML] A controlled quasi-experimental study of an educational intervention to reduce the unnecessary use of antimicrobials for asymptomatic bacteriuria

N Irfan, A Brooks, S Mithoowani, SJ Celetti, C Main… - PLoS …, 2015 - journals.plos.org
Background Asymptomatic bacteriuria (ABU) should only be treated in cases of pregnancy
or in-patients undergoing urologic procedures; however, unnecessary treatment of ABU is …

[HTML][HTML] Management of major bleeds in patients with immune thrombocytopenia

S Mithoowani, A Cervi, N Shah, R Ejaz… - Journal of Thrombosis …, 2020 - Elsevier
Background A standard approach to the recognition and management of major bleeding in
immune thrombocytopenia (ITP) is lacking. Methods Retrospective cohort study of ITP …

Pharmacokinetics of direct oral anticoagulants after bariatric surgery: A retrospective cohort study

…, EK Tseng, AG Doumouras, S Mithoowani - Thrombosis …, 2024 - Elsevier
Bariatric surgery is being used with increasing frequency to prevent and treat health
complications associated with obesity [1]. Patients who have undergone bariatric surgery may …

Improving medical education in hematology and transfusion medicine in Canada: Standards and limitations

M Laureano, S Mithoowani, EK Tseng… - Advances in Medical …, 2021 - Taylor & Francis
The paradigm of medical education is evolving with the introduction of competency-based
medical education (CBME) and it is crucial that residency programs adapt. In this paper, we …

Adherence to apixaban for extended thromboprophylaxis after major abdominal or pelvic surgery for cancer: a prospective cohort study

…, N Sne, K Kahnamoui, S Mithoowani… - Journal of Surgical …, 2022 - Wiley Online Library
… A data safety monitoring board with two independent physicians (Siraj Mithoowani and Rick
Ikesaka) reviewed the data after every 10 patients completed Visit 3 (postoperative Days 28–…

Neutropenia

S Mithoowani, L Cameron, MA Crowther - CMAJ, 2022 - Can Med Assoc
… Competing interests: Siraj Mithoowani has received personal fees from Leo Pharma. Mark
Crowther has served on advisory boards for Precision Biologicals, Hemostasis Reference …