Technological advances have led to the introduction of next-generation sequencing (NGS)
platforms in cancer investigation. NGS allows massive parallel sequencing that affords …

Simple Summary A clinical decision and study design investigating the level and extent of
angiogenesis modulation aimed at vascular normalization without rendering tissues hypoxic is …

Lung cancer is the main cause of cancer incidence and mortality worldwide and the
identification of clinically useful biomarkers for lung cancer detection at both early and metastatic …

Background The immunotherapy with immune checkpoints inhibitors (ICI) has changed the
life expectancy in metastatic melanoma (MM) patients. Nevertheless, several patients do not …

The latest member of the Coronaviridae family, called SARS-CoV-2, causes the Coronavirus
Disease 2019 (COVID-19). The disease has caused a pandemic and is threatening global …

Background NGS technology represents a powerful alternative to the standard Sanger
sequencing in the context of clinical setting. The proprietary software that are generally used for …

Over the past several years there has been much debate with regards to the prognostic and
clinical significance of pancreatic ductal adenocarcinoma (PDAC) with lymph nodes …

Despite the search for new therapeutic strategies for gastric cancer (GC), there is much
evidence of progression due to resistance to chemotherapy. Multidrug resistance (MDR) is the …

Interactions of malignant multiple myeloma (MM) plasma cells with the microenvironment
control MM plasma-cell growth, survival, drug-resistance and dissemination. As microvascular …

The coronavirus disease-2019 (COVID-19) pandemic has caused an enormous loss of lives.
Various clinical trials of vaccines and drugs are being conducted worldwide; nevertheless, …