Methods A hybrid approach based on established processes described by Glaser15 and by
the National Institutes of Health (http://prevention. nih. gov/cdp/about. aspx) 16 was used to …

Stroke is the second leading cause of death and the third leading cause of disability worldwide
and its burden is increasing rapidly in low-income and middle-income countries, many of …

Background Trials examining the benefit of thrombectomy in anterior circulation proximal
large vessel occlusion stroke have enrolled patients considered to have salvageable brain …

Background Among patients with acute ischemic stroke due to occlusions in the proximal
anterior intracranial circulation, less than 40% regain functional independence when treated …

Background The effect of endovascular thrombectomy that is performed more than 6 hours
after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is …

… Dr Nogueira reports receiving fees for service on steering and data safety monitoring
committees to Medtronic, Stryker, Penumbra, and Rapid Medical. Dr Demchuk reports receiving …

Background The Solitaire Flow Restoration Device is a novel, self-expanding stent retriever
designed to yield rapid flow restoration in acute cerebral ischaemia. We compared the …

Background Data from trials investigating the effects and risks of endovascular thrombectomy
for the treatment of stroke due to basilar-artery occlusion are limited. Methods We …

Background Present mechanical devices are unable to achieve recanalisation in up to 20–40%
of large vessel occlusion strokes. We compared efficacy and safety of the Trevo Retriever…

Background Previous randomised trials have shown an overwhelming benefit of mechanical
thrombectomy for treating patients with stroke caused by large vessel occlusion of the …