User profiles for Peter Senior

Peter Senior

Alberta Diabetes Institute, University of Alberta
Verified email at ualberta.ca
Cited by 13452

Five-year follow-up after clinical islet transplantation

EA Ryan, BW Paty, PA Senior, D Bigam, E Alfadhli… - Diabetes, 2005 - Am Diabetes Assoc
Islet transplantation can restore endogenous β-cell function to subjects with type 1 diabetes.
Sixty-five patients received an islet transplant in Edmonton as of 1 November 2004. Their …

The role and regulation of energy reserve polymers in micro-organisms

EA Dawes, PJ Senior - Advances in microbial physiology, 1973 - Elsevier
Publisher Summary This chapter focuses on the polymeric reserve materials and thus
excludes the consideration of lipids other than poly-β-hydroxybutyrate, and the disaccharide …

Improvement in outcomes of clinical islet transplantation: 1999–2010

…, T Berney, A Secchi, S Messinger, PA Senior… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE To describe trends of primary efficacy and safety outcomes of islet transplantation
in type 1 diabetes recipients with severe hypoglycemia from the Collaborative Islet …

Ethnicity as a variable in epidemiological research

PA Senior, R Bhopal - Bmj, 1994 - bmj.com
Ethnicity is used increasingly as a key variable to describe health data, and ethnic monitoring
in the NHS will further stimulate this trend. We identify four fundamental problems with …

Phase 3 trial of transplantation of human islets in type 1 diabetes complicated by severe hypoglycemia

…, MR Rickels, C Ricordi, MA Robien, PA Senior… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Impaired awareness of hypoglycemia (IAH) and severe hypoglycemic events (SHEs)
cause substantial morbidity and mortality in patients with type 1 diabetes (T1D). …

[HTML][HTML] Guidelines for the management of chronic kidney disease

…, S Klarenbach, B Barrett, R Foley, K Jindal, P Senior… - Cmaj, 2008 - Can Med Assoc
New guidelines for the management of chronic kidney disease have been developed by the
Canadian Society of Nephrology (Appendix 1 contains the fulltext guidelines; available at …

The regulation of poly-β-hydroxybutyrate metabolism in Azotobacter beijerinckii

PJ Senior, EA Dawes - Biochemical Journal, 1973 - portlandpress.com
1. The enzymes β-ketothiolase, acetoacetyl-CoA reductase, acetoacetate–succinate CoA-transferase
(`thiophorase') and d(−)-3-hydroxybutyrate dehydrogenase have been partially …

Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation

EA Ryan, T Shandro, K Green, BW Paty, PA Senior… - Diabetes, 2004 - Am Diabetes Assoc
Currently, the major indications for solitary islet transplantation are recurrent severe hypoglycemia
and labile glucose control. Quantifying these problems remains subjective. We have …

[HTML][HTML] Serum urate lowering with allopurinol and kidney function in type 1 diabetes

…, WN Robiner, SE Rosas, P Senior… - … England Journal of …, 2020 - Mass Medical Soc
Background Higher serum urate levels are associated with an increased risk of diabetic kidney
disease. Lowering of the serum urate level with allopurinol may slow the decrease in the …

[HTML][HTML] Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors

…, A Kelly, A King, A Mo, L Page, P Richardson, P Senior… - The Lancet, 2017 - thelancet.com
Background Limits on the frequency of whole blood donation exist primarily to safeguard
donor health. However, there is substantial variation across blood services in the maximum …