User profiles for Pascal M. Lavoie

Pascal Lavoie

Professor, University of British Columbia
Verified email at cw.bc.ca
Cited by 6262

[HTML][HTML] Maternal immunological adaptation during normal pregnancy

…, C Michalski, M Sadarangani, PM Lavoie - Frontiers in …, 2020 - frontiersin.org
The risk and severity of specific infections are increased during pregnancy due to a
combination of physiological and immunological changes. Characterizing the maternal immune …

Neonatal innate TLR-mediated responses are distinct from those of adults

…, F Thommai, XY Wang, PM Lavoie… - The Journal of …, 2009 - journals.aai.org
The human neonate and infant are unduly susceptible to infection with a wide variety of
microbes. This susceptibility is thought to reflect differences from adults in innate and adaptive …

Heritability of bronchopulmonary dysplasia, defined according to the consensus statement of the national institutes of health

PM Lavoie, C Pham, KL Jang - Pediatrics, 2008 - publications.aap.org
OBJECTIVE. The goal was to determine the magnitude of genetic effects on susceptibility
and risk factors for bronchopulmonary dysplasia by using the clinically validated National …

[HTML][HTML] Neonatal sepsis due to coagulase-negative staphylococci

…, GK Boyce, M Sadarangani, PM Lavoie - Journal of Immunology …, 2013 - hindawi.com
Neonates, especially those born prematurely, are at high risk of morbidity and mortality from
sepsis. Multiple factors, including prematurity, invasive life-saving medical interventions, and …

The developing human preterm neonatal immune system: a case for more research in this area

AA Sharma, R Jen, A Butler, PM Lavoie - Clinical immunology, 2012 - Elsevier
Neonates, particularly those born prematurely, are among the most vulnerable age group
for morbidity and mortality due to infections. Immaturity of the innate immune system and a …

Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells

…, A Kallos, J Crabtree, A Rein-Weston, PM Lavoie… - PloS one, 2010 - journals.plos.org
Newborns and young infants suffer increased infectious morbidity and mortality as compared
to older children and adults. Morbidity and mortality due to infection are highest during the …

Waning immunity against respiratory syncytial virus during the coronavirus disease 2019 pandemic

…, I Sekirov, DJ Marchant, PM Lavoie - The Journal of …, 2022 - academic.oup.com
Health jurisdictions have seen a near-disappearance of respiratory syncytial virus (RSV)
during the first year of the coronavirus disease 2019 (COVID-19) pandemic. Over this …

Immunogenicity of extended mRNA SARS-CoV-2 vaccine dosing intervals

…, L Golding, TL Kirkham, PA Demers, PM Lavoie - Jama, 2022 - jamanetwork.com
Methods| The COVID-19 Occupational Risks, Seroprevalence and Immunity among Paramedics
in Canada cohort study (approved by the University of British Columbia and University …

A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor β chain and major histocompatibility complex class II

L Leder, A Llera, PM Lavoie, MI Lebedeva… - The Journal of …, 1998 - rupress.org
The three-dimensional structure of the complex between a T cell receptor (TCR) β chain (mouse
Vβ8.2Jβ2.1Cβ1) and the superantigen (SAG) staphylococcal enterotoxin C3 (SEC3) …

An immunological perspective on neonatal sepsis

B Kan, HR Razzaghian, PM Lavoie - Trends in molecular medicine, 2016 - cell.com
Despite concerted international efforts, mortality from neonatal infections remains unacceptably
high in some areas of the world, particularly for premature infants. Recent developments …