Background Optimal extent of surgical resection (EOR) of high-grade gliomas (HGGs) remains
uncertain in the elderly given the unclear benefits and potentially higher rates of mortality …

BACKGROUND Ischemic stroke is a leading cause of death and disability worldwide. Much
of the long-term disability occurs in patients with Emergent Large Vessel Occlusion (ELVO). …

Background Brain metastases are most common in adults with lung cancer, predicting
uniformly poor patient outcome, with a median survival of only months. Despite their frequency …

The master regulatory gene Bmi1 modulates key stem cell properties in neural precursor
cells (NPCs), and has been implicated in brain tumorigenesis. We previously identified a …

BACKGROUND AND PURPOSE: Denser coil packing in intracranial aneurysms is believed
to result in lower recanalization rates. Hydrogel-coated expandable coils (HydroCoil) …

Background Ischemic stroke is a leading cause of death and disability worldwide. Much of
the long-term disability occurs in patients with Emergent Large Vessel Occlusion (ELVO). In …

… Paula Klurfan1,2, … Hazard ratios (HR) with 95% CIs and p values were reported. The level
of … (HR 1.8; 95% CI 1.2 to 2.6, p=0.002), which translates into an approximately twice higher …

Background Transfemoral approach for endovascular interventions is not always possible
in cases of unfavorable anatomy. We report our experience using a transcervical approach …

Epistaxis is a common disorder affecting equally both genders. Posterior origin of epistaxis
in some instances requires endovascular treatment. Anastomoses between external carotid …

Methods The University of Toronto Brain Vascular Malformation Group keeps a database on
all BAVM patients evaluated and treated by the group. The data was collected …