Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study

…, G Batist, T Bekaii-Saab, MA Bilen, N Bouganim… - The Lancet, 2020 - thelancet.com
Background Data on patients with COVID-19 who have cancer are lacking. Here we characterise
the outcomes of a cohort of patients with cancer and COVID-19 and identify potential …

Use of conjoint analysis to assess breast cancer patient preferences for chemotherapy side effects

…, S Mazzarello, S Dent, S Gertler, N Bouganim… - The …, 2014 - academic.oup.com
Objective. Our objective was to evaluate preferences associated with grade I/II and grade III/IV
chemotherapy side effects among breast cancer patients receiving chemotherapy. We …

[HTML][HTML] Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors

…, J Lafleur, NR Bertos, J Asselah, N Bouganim… - Communications …, 2020 - nature.com
Subsets of breast tumors present major clinical challenges, including triple-negative,
metastatic/recurrent disease and rare histologies. Here, we developed 37 patient-derived …

[HTML][HTML] Durvalumab for recurrent or metastatic head and neck squamous cell carcinoma: Results from a single-arm, phase II study in patients with≥ 25% tumour cell …

…, A Jimeno, JS Good, J Fayette, N Bouganim… - European journal of …, 2019 - Elsevier
Background Patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M
HNSCC) progressing on platinum-based chemotherapy have poor prognoses and limited …

Changes in lung cancer treatment as a result of the coronavirus disease 2019 pandemic

A Elkrief, S Kazandjian, N Bouganim - JAMA oncology, 2020 - jamanetwork.com
Methods| We prospectively assessed the treatment plan of all patients seen in the thoracic
oncology clinic at the McGill University Health Centre (MUHC) between March 2 and May 30, …

Aromatase inhibitors and the risk of cardiovascular outcomes in women with breast cancer: a population-based cohort study

F Khosrow-Khavar, KB Filion, N Bouganim, S Suissa… - Circulation, 2020 - Am Heart Assoc
Background: The association between aromatase inhibitors and cardiovascular outcomes
among women with breast cancer is controversial. Given the discrepant findings from …

[HTML][HTML] High mortality among hospital-acquired COVID-19 infection in patients with cancer: a multicentre observational cohort study

…, JM Loree, WH Miller Jr, DC Vinh, N Bouganim… - European Journal of …, 2020 - Elsevier
Introduction Studies suggest that patients with cancer are more likely to experience severe
outcomes from COVID-19. Therefore, cancer centres have undertaken efforts to care for …

A systemic inflammation response index (SIRI) correlates with survival and predicts oncological outcome for mFOLFIRINOX therapy in metastatic pancreatic cancer

…, J Asselah, O Donnay, G Zogopoulos, N Bouganim… - Pancreatology, 2020 - Elsevier
Objectives Systemic inflammatory response and survival has not been evaluated as a
predictive factor of chemotherapy in metastatic pancreatic cancer. The aim of this study was to …

Incretin based drugs and risk of cholangiocarcinoma among patients with type 2 diabetes: population based cohort study

…, JL Faillie, F Montastruc, RW Platt, N Bouganim… - bmj, 2018 - bmj.com
Objective To determine whether use of dipeptidyl peptidase-4 (DPP-4) inhibitors and
glucagon-like peptide-1 (GLP-1) receptor agonists are associated with an increased risk of …

A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination–deficient Pancreatic Cancer

…, Y Riazalhosseini, J Asselah, N Bouganim… - Clinical Cancer …, 2020 - AACR
Purpose: Pancreatic ductal adenocarcinoma (PDAC) arising in patients with a germline
BRCA1 or BRCA2 (gBRCA) mutation may be sensitive to platinum and PARP inhibitors (PARPi). …