[HTML][HTML] Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study

DN Juurlink, MM Mamdani, DS Lee… - … England Journal of …, 2004 - Mass Medical Soc
Background The Randomized Aldactone Evaluation Study (RALES) demonstrated that
spironolactone significantly improves outcomes in patients with severe heart failure. Use of …

[HTML][HTML] A population-based study of the drug interaction between proton pump inhibitors and clopidogrel

…, PC Austin, JV Tu, DA Henry, A Kopp, MM Mamdani - Cmaj, 2009 - Can Med Assoc
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active
metabolite. The clinical significance of this drug interaction is unknown. Methods: We …

Long-term analgesic use after low-risk surgery: a retrospective cohort study

A Alam, T Gomes, H Zheng, MM Mamdani… - Archives of internal …, 2012 - jamanetwork.com
Background This study evaluated the risk of long-term analgesic use after low-risk surgery
in older adults not previously prescribed analgesics. Methods We conducted a retrospective …

Chronic dialysis and death among survivors of acute kidney injury requiring dialysis

…, RR Quinn, J Luo, P Li, DC Scales, MM Mamdani… - Jama, 2009 - jamanetwork.com
Context Severe acute kidney injury among hospitalized patients often necessitates initiation
of short-term dialysis. Little is known about the long-term outcome of those who survive to …

Opioid dose and drug-related mortality in patients with nonmalignant pain

T Gomes, MM Mamdani, IA Dhalla… - Archives of internal …, 2011 - jamanetwork.com
Background Opioids are widely prescribed for chronic nonmalignant pain, often at doses
exceeding those recommended in clinical practice guidelines. However, the risk-benefit ratio of …

A comparison of propensity score methods: a case‐study estimating the effectiveness of post‐AMI statin use

PC Austin, MM Mamdani - Statistics in medicine, 2006 - Wiley Online Library
There is an increasing interest in the use of propensity score methods to estimate causal
effects in observational studies. However, recent systematic reviews have demonstrated that …

Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women

LY Park-Wyllie, MM Mamdani, DN Juurlink, GA Hawker… - Jama, 2011 - jamanetwork.com
Context Osteoporosis is associated with significant morbidity and mortality. Oral bisphosphonates
have become a mainstay of treatment, but concerns have emerged that long-term use …

The burden of opioid-related mortality in the United States

T Gomes, M Tadrous, MM Mamdani… - JAMA network …, 2018 - jamanetwork.com
Importance Opioid prescribing and overdose are leading public health problems in North
America, yet the precise public health burden has not been quantified. Objective To examine …

Risk of incident diabetes among patients treated with statins: population based study

…, X Camacho, DN Juurlink, BR Shah, MM Mamdani - Bmj, 2013 - bmj.com
Objective To examine the risk of new onset diabetes among patients treated with different
HMG-CoA reductase inhibitors (statins). Design Population based cohort study with time to …

Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone

IA Dhalla, MM Mamdani, MLA Sivilotti, A Kopp… - Cmaj, 2009 - Can Med Assoc
Introduction: Opioid-related mortality appears to be increasing in Canada. We examined the
true extent of the problem and the impact of the introduction of long-acting oxycodone. …