Due to practical and ethical concerns associated with human experimentation, animal
models have been essential in cancer research. However, the average rate of successful …

BACKGROUND. The use of adjuvant chemotherapy to treat adults with localized resectable
soft‐tissue sarcoma remains controversial. The objective of this systematic review was to …

Musculoskeletal infections (MSKI) remain the bane of orthopedic surgery, and result in grievous
illness and inordinate costs that threaten healthcare systems. As prevention, diagnosis, …

Background: The presence of a pathologic fracture in an osteosarcoma has been considered
a poor prognostic factor and an indication for immediate amputation. The purpose of the …

Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account
for 5–10% of all STS. Synovial sarcoma differs from other STS by the relatively young age …

The records of 99 patients treated at one institution for osseous metastases secondary to
renal cell carcinoma were reviewed. Patients were followed up for at least 24 months or until …

Background context Randomized controlled trials (RCTs) are the most trustworthy source
for evaluating treatment effects, but RCTs of spine surgery interventions often produce …

Background Objectives of this study were to evaluate oncologic outcomes and to provide
guidelines for the management of primary myxoid (MLS) and round cell liposarcoma (RCLS). …

Background Limb salvage surgery (LSS) with endoprosthetic replacement is the most common
method of reconstruction following bone tumor resection in the adult population. The risk …

Background: Giant cell tumor of bone is a primary bone tumor that is treated surgically and is
associated with high morbidity in many cases. This tumor consists of giant cells expressing …