Humans expressing a defective form of the transcription factor AIRE (autoimmune regulator)
develop multiorgan autoimmune disease. We used aire- deficient mice to test the …

Appropriate use and interpretation of serological tests for assessments of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and potential immunity …

The prevention of autoimmunity requires the elimination of self-reactive T cells during their
development and maturation. The expression of diverse self-antigens by stromal cells in the …

The expression of self-antigen in the thymus is believed to be responsible for the deletion of
autoreactive T lymphocytes, a critical process in the maintenance of unresponsiveness to …

▪ Abstract Autoimmunity is a complex process that likely results from the summation of
multiple defective tolerance mechanisms. The NOD mouse strain is an excellent model of …

Multiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive
lymphocytes attack the myelin sheath of the central nervous system. B lymphocytes in the …

Neutralizing autoantibodies against type I interferons (IFNs) have been found in some patients
with critical coronavirus disease 2019 (COVID-19), the disease caused by severe acute …

An atomic force microscope (AFM) tip has been used to selectively produce surface
enhanced Raman scattering (SERS) for localized Raman spectroscopy. Spectra of thin films, …

The mutualistic relationship of gut-resident microbiota and the host immune system promotes
homeostasis that ensures maintenance of the microbial community and of a largely non-…

Autoimmune Polyendocrine Syndromes Autoimmune polyendocrine syndromes comprise a
diverse group of clinical entities involving functional impairment of multiple endocrine …