Although the application of the concept of a threshold to risk assessment is widespread,
there remains little experimental evidence for the existence of thresholds for genotoxic …

Objective: Women are 4 to 8 times more likely to sustain a serious knee injury than their
male counterparts. Previous studies have found that female sex steroids affect ligamentous …

The robust control of genotoxic N-nitrosamine (NA) impurities is an important safety
consideration for the pharmaceutical industry, especially considering recent drug product …

Background: Technological innovation is a key component of orthopaedic surgery. With the
integration of powerful technologies in surgery and clinical practice, artificial intelligence (AI) …

Background: Patients undergoing hip or knee replacement are at high risk of developing a
postoperative venous thromboembolism even after discharge from hospital. We sought to …

Background: The recent emphasis on anatomic reconstruction of the anterior cruciate
ligament (ACL) is well supported by clinical and biomechanical research. Unfortunately, the …

Background: Lipoma arborescens is a rare, intra-articular benign lesion characterized by
hyperplastic formation of villous projections that commonly presents as nonspecific mechanical …

Background: Anatomic anterior cruciate ligament (ACL) reconstruction improves knee
kinematics and joint stability in symptomatic patients who have ACL deficiency. Despite a …

Background: Supervised machine learning models in artificial intelligence (AI) have been
increasingly used to predict different types of events. However, their use in orthopaedic …

Background: Hemiarthroplasty is often the treatment of choice after hip fracture, particularly
in frail elderly patients. Such patients may benefit from home care after discharge. We …