BACKGROUND: To mitigate the effects of coronavirus disease 2019 (COVID-19), jurisdictions
worldwide ramped down nonemergent surgeries, creating a global surgical backlog. We …

… Oriana Yu, Maria Eberg, Samy Suissa, and Laurent Azoulay, Centre for Clinical …
Financial support: Laurent Azoulay Collection and assembly of data: Maria Eberg, Samy …

Background— Although the efficacy and safety of smoking cessation interventions are well
established, their efficacy and safety in patients with cardiovascular disease (CVD) remain …

Importance The COVID-19 pandemic has impacted cancer systems worldwide. Quantifying
the changes is critical to informing the delivery of care while the pandemic continues, as well …

Introduction Structural changes in the heart are known risk factors for atrial fibrillation (AF).
An association between high-sensitivity cardiac troponin T (hs-cTnT), a marker of myocardial …

Background Hypertensive disorders in pregnancy ( HDP ) have been shown to predict later
risk of cardiovascular disease ( CVD ). However, previous studies have not accounted for …

Clinical pathways outline standardized processes in the delivery of care for a specific disease.
Patient journeys through the healthcare system, however, can deviate substantially from …

Apixaban is one of the new oral anticoagulants, which is prescribed as an alternative to vitamin
K antagonists (VKAs). Concerns regarding its bleeding profile persist and require further …

Background: Chest pain is one of the most common reasons for emergency department (ED)
visits in developed countries. Whether higher volume EDs have better outcomes, …

Background— Stenting is an endovascular alternative to endarterectomy for the management
of carotid stenosis, but its long-term safety and efficacy relative to endarterectomy remain …