To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC),
we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …

Survival after a diagnosis of ovarian cancer has not improved, and despite histological
differences, treatment is similar for all cases. Understanding the molecular basis for ovarian …

… Madalene A. Earp … Administrative, technical, or material support (ie, reporting or
organizing data, constructing databases): DJ Hazelett, MA Earp, SJ Ramus …

Epithelial ovarian cancer (EOC) is a heterogeneous cancer with both genetic and environmental
risk factors. Variants influencing the risk of developing the less-common EOC subtypes …

Gene fusions play a critical role in some cancers and can serve as important clinical targets.
In epithelial ovarian cancer (EOC), the contribution of fusions, especially by histological type…

Background The Goals of Care Designation (GCD) is a medical order used to communicate
the focus of a patient’s care in Alberta, Canada. In this study, we aimed to determine the …

Background Mitochondria are the site of oxidative phosphorylation, a process which
generates reactive oxygen species (ROS). Elevated ROS levels can lead to oxidative stress, a …

Background Until recently, genome-wide association studies (GWAS) have been restricted
to research groups with the budget necessary to genotype hundreds, if not thousands, of …

Background: While numerous susceptibility loci for epithelial ovarian cancer (EOC) have
been identified, few associations have been reported with overall survival. In the absence of …

STUDY QUESTION Do differences in heritable genetic factors explain some of the difference
in age at natural menopause (ANM) among populations? SUMMARY ANSWER One single …