[HTML][HTML] Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China
…, Z Wu, Z Yu, W Zhang, Q Zhong, X Zheng, L Sang… - Annals of intensive …, 2020 - Springer
Background The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all
over the world, posing a great pressure on critical care resources due to large number of …
over the world, posing a great pressure on critical care resources due to large number of …
[HTML][HTML] Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis
Background The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide.
Objective To evaluate the risk of serious adverse outcomes in patients with COVID-19 by …
Objective To evaluate the risk of serious adverse outcomes in patients with COVID-19 by …
[HTML][HTML] Kinetics of viral load and antibody response in relation to COVID-19 severity
Y Wang, L Zhang, L Sang, F Ye, S Ruan… - The Journal of …, 2020 - Am Soc Clin Investig
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent for
coronavirus 2019 (COVID-19) pneumonia. Little is known about the kinetics, tissue distribution…
coronavirus 2019 (COVID-19) pneumonia. Little is known about the kinetics, tissue distribution…
Development and validation of a clinical risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19
…, A Chen, C Li, Y Li, W Guan, L Sang… - JAMA internal …, 2020 - jamanetwork.com
Importance Early identification of patients with novel coronavirus disease 2019 (COVID-19)
who may develop critical illness is of great importance and may aid in delivering proper …
who may develop critical illness is of great importance and may aid in delivering proper …
Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a nationwide analysis in China
…, M Jiang, W Guan, C Zhan, T Wang, C Tang, L Sang… - Chest, 2020 - Elsevier
Background The novel coronavirus disease 2019 (COVID-19) has become a global health
emergency. The cumulative number of new confirmed cases and deaths are still increasing …
emergency. The cumulative number of new confirmed cases and deaths are still increasing …
The E2F1–3 transcription factors are essential for cellular proliferation
L Wu, C Timmers, B Maiti, HI Saavedra, L Sang… - Nature, 2001 - nature.com
The retinoblastoma tumour suppressor (Rb) pathway is believed to have a critical role in the
control of cellular proliferation by regulating E2F activities 1 , 2 . E2F1, E2F2 and E2F3 …
control of cellular proliferation by regulating E2F activities 1 , 2 . E2F1, E2F2 and E2F3 …
[HTML][HTML] Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicentre) and outside Hubei (non-epicentre): a nationwide …
…, Y Li, H Liang, Y Zhao, X Liu, L Sang… - European …, 2020 - Eur Respiratory Soc
Background During the outbreak of coronavirus disease 2019 (COVID-19), consistent and
considerable differences in disease severity and mortality rate of patients treated in Hubei …
considerable differences in disease severity and mortality rate of patients treated in Hubei …
Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China
R Chen, L Sang, M Jiang, Z Yang, N Jia, W Fu… - Journal of Allergy and …, 2020 - Elsevier
Background Crucial roles of hematologic and immunologic responses in progression of
coronavirus disease 2019 (COVID-19) remain largely unclear. Objective We sought to address …
coronavirus disease 2019 (COVID-19) remain largely unclear. Objective We sought to address …
[HTML][HTML] Ferroptosis, pyroptosis and necroptosis in acute respiratory distress syndrome
Y Zheng, Y Huang, Y Xu, L Sang, X Liu, Y Li - Cell Death Discovery, 2023 - nature.com
Acute respiratory distress syndrome (ARDS) is an acute and uncontrolled pulmonary
inflammation caused by various insults. Cell death is a critical mechanism in the pathogenesis of …
inflammation caused by various insults. Cell death is a critical mechanism in the pathogenesis of …
[HTML][HTML] Early triage of critically ill COVID-19 patients using deep learning
…, W Tang, W Guan, Z Chen, Y Zhao, L Sang… - Nature …, 2020 - nature.com
The sudden deterioration of patients with novel coronavirus disease 2019 (COVID-19) into
critical illness is of major concern. It is imperative to identify these patients early. We show that …
critical illness is of major concern. It is imperative to identify these patients early. We show that …