[HTML][HTML] Stress and breast cancer: from epidemiology to molecular biology

L Antonova, K Aronson, CR Mueller - Breast Cancer Research, 2011 - Springer
Stress exposure has been proposed to contribute to the etiology of breast cancer. However,
the validity of this assertion and the possible mechanisms involved are not well established. …

Hydrocortisone down‐regulates the tumor suppressor gene BRCA1 in mammary cells: A possible molecular link between stress and breast cancer

L Antonova, CR Mueller - Genes, Chromosomes and Cancer, 2008 - Wiley Online Library
Psychological stress has been correlated with breast cancer development in numerous
epidemiological studies. However, physiological and molecular models which may account for …

The Unliganded Glucocorticoid Receptor Positively Regulates the Tumor Suppressor Gene BRCA1 through GABP Beta

HD Ritter, L Antonova, CR Mueller - Molecular Cancer Research, 2012 - AACR
Loss of BRCA1 tumor suppressor function is a critical event in breast tumorigenesis. We have
previously identified the stress hormone hydrocortisone as a negative regulator of BRCA1 …

Measures of trainee performance in advanced endoscopy: a systematic review

PD James, L Antonova, M Martel, A Barkun - Best Practice & Research …, 2016 - Elsevier
Introduction The diversity, technical skills required, and risk inherent to advanced endoscopy
techniques all contribute to complex training curricula and steep learning curves. Since …

[HTML][HTML] Comparison of socio-economic determinants of COVID-19 testing and positivity in Canada: A multi-provincial analysis

L Antonova, C Somayaji, J Cameron, M Sirski… - PloS one, 2023 - journals.plos.org
Background The effects of the COVID-19 pandemic have been more pronounced for socially
disadvantaged populations. We sought to determine how access to SARS-CoV-2 testing …

Health care utilization and costs for patients with end-stage liver disease are significantly higher at the end of life compared to those of other decedents

EM Kelly, PD James, S Murthy, L Antonova… - Clinical …, 2019 - Elsevier
Background & Aims Patients with end-stage liver disease (ESLD) have progressively complex
medical needs. However, little is known about their end-of-life health care utilization or …

[HTML][HTML] A randomized clinical prospective trial comparing split-dose picosulfate/magnesium citrate and polyethylene glycol for colonoscopy preparation

A Rostom, C Dube, K Bishay, L Antonova, SJ Heitman… - PLoS …, 2019 - journals.plos.org
Background Colonoscopy remains the gold standard for the investigation of abnormalities
within the colon. However, its success is highly dependent on the quality of bowel preparation. …

[HTML][HTML] Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity

R Sriram, V Lo, B Pryce, L Antonova, AJ Mears… - Breast Cancer …, 2015 - Springer
Introduction Periostin (Postn) is a secreted cell adhesion protein that activates signaling
pathways to promote cancer cell survival, angiogenesis, invasion, and metastasis. Interestingly, …

[HTML][HTML] Variable endoscopist performance in proximal and distal adenoma detection during colonoscopy: a retrospective cohort study

P James, M Hegagi, M Hegagi, L Antonova… - BMC …, 2018 - Springer
Background Adenoma Detection Rate (ADR) is a validated colonoscopy quality indicator. In
addition to overall ADR, Distal and Proximal Adenoma Detection Rates may provide …

[HTML][HTML] Long-term outcomes of liver transplant recipients followed up in non-transplant centres: Care closer to home

…, SV Venkatachalapathy, IN Guha, L Antonova… - Clinical …, 2021 - ncbi.nlm.nih.gov
Methods A retrospective analysis of all adult patients who underwent liver transplantation
between 1987 and 2016, with post-transplant follow-up in two non-transplant centres in the UK …