User profiles for Leah Soriaga

Leah Barrera Soriaga

Bioinformatics
Verified email at perceptrove.com
Cited by 17350

[HTML][HTML] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

…, AE Powell, A Chen, C Maher, L Yin, D Sun, L Soriaga… - Nature, 2022 - nature.com
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …

[HTML][HTML] Domestication and divergence of Saccharomyces cerevisiae beer yeasts

B Gallone, J Steensels, T Prahl, L Soriaga, V Saels… - Cell, 2016 - cell.com
Whereas domestication of livestock, pets, and crops is well documented, it is still unclear to
what extent microbes associated with the production of food have also undergone human …

The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2

…, S Ledoux, Y Kawaoka, A Werts, C Colas, L Soriaga… - biorxiv, 2021 - biorxiv.org
VIR-7831 and VIR-7832 are dual action monoclonal antibodies (mAbs) targeting the spike
glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). VIR-7831 …

Phylogenetic distribution of CRISPR-Cas systems in antibiotic-resistant Pseudomonas aeruginosa

A van Belkum, LB Soriaga, MC LaFave, S Akella… - MBio, 2015 - Am Soc Microbiol
Pseudomonas aeruginosa is an antibiotic-refractory pathogen with a large genome and
extensive genotypic diversity. Historically, P. aeruginosa has been a major model system for …

Membrane lectins enhance SARS-CoV-2 infection and influence the neutralizing activity of different classes of antibodies

FA Lempp, L Soriaga, M Montiel-Ruiz, F Benigni… - bioRxiv, 2021 - biorxiv.org
Investigating the mechanisms of SARS-CoV-2 cellular infection is key to better understand
COVID-19 immunity and pathogenesis. Infection, which involves both cell attachment and …

[HTML][HTML] Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies

FA Lempp, LB Soriaga, M Montiel-Ruiz, F Benigni… - Nature, 2021 - nature.com
SARS-CoV-2 infection—which involves both cell attachment and membrane fusion—relies
on the angiotensin-converting enzyme 2 (ACE2) receptor, which is paradoxically found at low …

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

…, GD De Melo, L Kergoat, H Bourhy, J Neyts, L Soriaga… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator

I Ajjawi, J Verruto, M Aqui, LB Soriaga… - Nature …, 2017 - nature.com
Lipid production in the industrial microalga Nannochloropsis gaditana exceeds that of
model algal species and can be maximized by nutrient starvation in batch culture. However, …

Predicting the mutational drivers of future SARS-CoV-2 variants of concern

…, S Weaver, J Di Iulio, E Ferri, L Soriaga… - Science translational …, 2022 - science.org
SARS-CoV-2 evolution threatens vaccine- and natural infection–derived immunity and the
efficacy of therapeutic antibodies. To improve public health preparedness, we sought to …

Refined Pichia pastoris reference genome sequence

…, S Trstenjak, A Schiefer, T Richardson, L Soriaga… - Journal of …, 2016 - Elsevier
Strains of the species Komagataella phaffii are the most frequently used “Pichia pastoris”
strains employed for recombinant protein production as well as studies on peroxisome …