It is common in population screening surveys or in the investigation of new diagnostic tests
to have results from one or more tests investigating the same condition or disease, none of …

Many analyses of results from multiple diagnostic tests assume the tests are statistically
independent conditional on the true disease status of the subject. This assumption may be …

Background: Cystatin C (CysC) may be a better marker of glomerular filtration rate (GFR) than
serum creatinine (SCr) level. Few studies derived CysC-based GFR prediction equations …

Sample size estimation is a major component of the design of virtually every experiment in
medicine. Prudent use of the available prior information is a crucial element of experimental …

Receiver operating characteristic (ROC) analysis, which yields indices of accuracy such as
the area under the curve (AUC), is increasingly being used to evaluate the performances of …

Planning studies involving diagnostic tests is complicated by the fact that virtually no test
provides perfectly accurate results. The misclassification induced by imperfect sensitivities and …

Objectives : We sought to conduct a systematic review and meta-analysis of the cardiovascular
risk associated with the metabolic syndrome as defined by the 2001 National Cholesterol …

Objective To examine mortality rates in the largest systemic lupus erythematosus (SLE) cohort
ever assembled. Methods Our sample was a multisite international SLE cohort (23 centers…

This article describes research criteria and probability methodology for the diagnosis of
prodromal PD. Prodromal disease refers to the stage wherein early symptoms or signs of PD …

Objective: The objective of this study was to evaluate the concordance of self-report measures
of medication adherence (interview, diary, or questionnaire) with nonself-report measures …