Background: The use of proton pump inhibitors has been associated with an increased risk
of hip fracture. We sought to further explore the relation between duration of exposure to …

ContextLimited evidence exists to guide the optimal frequency of repeat endoscopic
examination for colorectal cancer screening after a negative colonoscopy.ObjectiveTo determine …

Background & Aims The management of inflammatory bowel disease (IBD) poses a particular
challenge during pregnancy because the health of both the mother and the fetus must be …

Background & Aims The medical management of ulcerative colitis (UC) has improved through
the development of new therapies and novel approaches that optimize existing drugs. …

Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

… Otley, Greg Rosenfeld, Juan Nicolás Peña-Sánchez, and Laura E. Targownik contributed
to study design, data acquisition, critical revision of the manuscript for important intellectual …

Objectives: The incidence of pediatric-onset inflammatory bowel disease (IBD) is increasing
worldwide. We used population-based health administrative data to determine national …

BACKGROUNDS & AIMS: Recent studies have shown an association between proton-pump
inhibitor use (PPI) and hip fracture. The mechanism by which PPI use promotes the …

OBJECTIVES: Previous studies have reported colectomy rates of over 50% in ulcerative
colitis (UC), although changes in management may have influenced the rates of colectomy in …

Objective The microbiome contributes to the pathogenesis of inflammatory bowel disease (IBD)
but the relative contribution of different lifestyle and environmental factors to the …