Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid …

…, D Suryanarayan, M Almarshoodi, LA Castellucci… - bmj, 2021 - bmj.com
Objective To evaluate the effects of therapeutic heparin compared with prophylactic heparin
among moderately ill patients with covid-19 admitted to hospital wards. Design Randomised …

Pulmonary embolism: update on management and controversies

L Duffett, LA Castellucci, MA Forgie - Bmj, 2020 - bmj.com
Pulmonary embolism is a common and potentially fatal cardiovascular disorder that must be
promptly diagnosed and treated. The diagnosis, risk assessment, and management of …

Efficacy and safety outcomes of oral anticoagulants and antiplatelet drugs in the secondary prevention of venous thromboembolism: systematic review and network …

LA Castellucci, C Cameron, G Le Gal, MA Rodger… - Bmj, 2013 - bmj.com
Objective To summarise and compare the efficacy and safety of various oral anticoagulants (dabigatran,
rivaroxaban, apixaban, and vitamin K antagonists) and antiplatelet agents (…

[HTML][HTML] Therapeutic plasma exchange in vaccine-induced immune thrombotic thrombocytopenia

…, G Roberge, M Carrier, LA Castellucci… - … England Journal of …, 2021 - Mass Medical Soc
Therapeutic Plasma Exchange in Refractory VITT Three patients with severe manifestations
of VITT after Covid-19 vaccination had a poor response to initial therapy with anticoagulants …

Clinical and safety outcomes associated with treatment of acute venous thromboembolism: a systematic review and meta-analysis

LA Castellucci, C Cameron, G Le Gal, MA Rodger… - Jama, 2014 - jamanetwork.com
Importance Many anticoagulant strategies are available for the treatment of acute venous
thromboembolism, yet little guidance exists regarding which drug is most effective and safe. …

Efficacy and safety of anticoagulant therapy for the treatment of acute cancer-associated thrombosis: a systematic review and meta-analysis

M Carrier, C Cameron, A Delluc, L Castellucci… - Thrombosis research, 2014 - Elsevier
Background Current clinical practice guidelines all recommend the use of therapeutic doses
of low molecular weight heparins (LMWH) for the initial and long-term treatment of cancer-…

Medical masks versus N95 respirators for preventing COVID-19 among health care workers: a randomized trial

…, K Ali, S Mansour, LA Castellucci… - Annals of internal …, 2022 - acpjournals.org
Background: It is uncertain if medical masks offer similar protection against COVID-19 compared
with N95 respirators. Objective: To determine whether medical masks are noninferior to …

Canadian stroke best practice recommendations: Management of Spontaneous Intracerebral Hemorrhage, 7th Edition Update 2020

…, M Patrice Lindsay, LA Castellucci… - … journal of stroke, 2021 - journals.sagepub.com
Spontaneous intracerebral hemorrhage is a particularly devastating type of stroke with greater
morbidity and mortality compared with ischemic stroke and can account for half or more of …

Self-reported adherence to anticoagulation and its determinants using the Morisky medication adherence scale

LA Castellucci, J Shaw, K van Der Salm, P Erkens… - Thrombosis research, 2015 - Elsevier
Background Direct oral anticoagulants (DOACs) are used for treatment of venous thromboembolism
(VTE) and stroke prevention in atrial fibrillation (AF). Given the shorter half-life and …

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE)

…, E Worndl, S Go, K Mandelzweig, LA Castellucci… - bmj, 2022 - bmj.com
Objectives To assess the effectiveness of prone positioning to reduce the risk of death or
respiratory failure in non-critically ill patients admitted to hospital with covid-19. Design …