Ebola preparedness: a rapid needs assessment of critical care in a tertiary hospital

…, S Sutherland, N Robillard, J Kim, K Dupuis… - … Open Access Journal, 2015 - cmajopen.ca
Background: The current outbreak of Ebola has been declared a public health emergency of
international concern. We performed a rigorous and rapid needs assessment to identify the …

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

J Dupuis, C Langenberg, I Prokopenko, R Saxena… - Nature …, 2010 - nature.com
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

[HTML][HTML] The science performance of JWST as characterized in commissioning

…, R Douglas, K DuPrie, J Dupuis… - Publications of the …, 2023 - iopscience.iop.org
This paper characterizes the actual science performance of the James Webb Space Telescope
(JWST), as determined from the six month commissioning period. We summarize the …

[HTML][HTML] Potential role of deer tick virus in Powassan encephalitis cases in Lyme disease–endemic areas of New York, USA

…, JL White, BP Backenson, AP Dupuis… - Emerging infectious …, 2013 - ncbi.nlm.nih.gov
Powassan virus, a member of the tick-borne encephalitis group of flaviviruses, encompasses
2 lineages with separate enzootic cycles. The prototype lineage of Powassan virus (POWV) …

[HTML][HTML] Integrative genetic analysis illuminates ALS heritability and identifies risk genes

…, E Kabashi, E Storkebaum, C Sellier, L Dupuis - Nature …, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) has substantial heritability, in part shared with fronto-temporal
dementia (FTD). We show that ALS heritability is enriched in splicing variants and in …

Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections

AKM Furuya, D Hunt, KS George, AP Dupuis… - Clinical …, 2019 - portlandpress.com
Zika (ZIKV) and dengue (DENV) virus infections elicit a robust but cross-reactive antibody
response against the viral envelope protein, while antibody responses against non-structural …

[HTML][HTML] Development and clinical utility of a blood-based test service for the rapid identification of actionable mutations in non–small cell lung carcinoma

…, K Koch, A Weaver, S Cooper, N Dupuis… - The Journal of Molecular …, 2017 - Elsevier
Nearly 80% of cancer patients do not have genetic mutation results available at initial oncology
consultation; up to 25% of patients begin treatment before receiving their results. These …

[HTML][HTML] Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies

…, K Tanriverdi, JE Freedman, N Raghavachari, J Dupuis… - Genome biology, 2017 - Springer
… When comparing our results with those of Kirsten et al. [8] using the same approach, we
validated 58% of our eligible, independent lead cis-eQTLs and 6% of our trans-eQTLs. We …

[HTML][HTML] Effects of cost surface uncertainty on current density estimates from circuit theory

…, JE Baici, MGC Brown, C Cordes, AE Dupuis… - PeerJ, 2020 - peerj.com
Background Conservation practitioners are often interested in developing land use plans
that increase landscape connectivity, which is defined as the degree to which the landscape …

[HTML][HTML] Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

…, RJF Loos, DM Waterworth, JB Meigs, J Dupuis… - PLoS …, 2012 - journals.plos.org
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are
highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other …