User profiles for Kevin Antoine Brown

Kevin Antoine Brown

Scientist, Public Health Ontario | Associate Professor, University of Toronto
Verified email at oahpp.ca
Cited by 6430

Trends in antibiotic use and nosocomial pathogens in hospitalized veterans with pneumonia at 128 medical centers, 2006–2010

…, B Huttner, G Stoddard, KA Brown… - Clinical Infectious …, 2015 - academic.oup.com
Background. In 2005, pneumonia practice guidelines recommended broad-spectrum
antibiotics for patients with risk factors for nosocomial pathogens. The impact of these …

Antibiotic Prescribing Choices and Their Comparative C. Difficile Infection Risks: A Longitudinal Case-Cohort Study

KA Brown, B Langford, KL Schwartz… - Clinical Infectious …, 2021 - academic.oup.com
Background Antibiotic use is the strongest modifiable risk factor for the development of
Clostridioides difficile infection, but prescribers lack quantitative information on comparative risks …

Reducing unnecessary urine culturing and antibiotic overprescribing in long-term care: a before-and-after analysis

KA Brown, A Chambers, S MacFarlane… - … Open Access Journal, 2019 - cmajopen.ca
Background: Antibiotic use in long-term care homes is highly variable. High rates of antibiotic
use are associated with antibiotic resistance and Clostridium difficile infection. We asked 2 …

Virtual learning collaboratives to improve urine culturing and antibiotic prescribing in long-term care: controlled before-and-after study

A Chambers, C Chen, KA Brown… - BMJ Quality & …, 2022 - qualitysafety.bmj.com
Background Urine culturing practices are highly variable in long-term care and contribute to
overprescribing of antibiotics for presumed urinary tract infections. The purpose of this study …

The Urine-culturing Cascade: Variation in Nursing Home Urine Culturing and Association With Antibiotic Use and Clostridiodes difficile Infection

KA Brown, N Daneman, KL Schwartz… - Clinical Infectious …, 2020 - academic.oup.com
Background Rates of antibiotic use vary widely across nursing homes and cannot be explained
by resident characteristics. Antibiotic prescribing for a presumed urinary tract infection is …

Variation in empiric coverage versus detection of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in hospitalizations for community-onset …

BE Jones, KA Brown, MM Jones, BD Huttner… - infection control & …, 2017 - cambridge.org
OBJECTIVETo examine variation in antibiotic coverage and detection of resistant pathogens
in community-onset pneumonia.DESIGNCross-sectional study.SETTINGA total of 128 …

Regional variability in outpatient antibiotic use in Ontario, Canada: a retrospective cross-sectional study

KL Schwartz, C Achonu, KA Brown… - … Open Access Journal, 2018 - cmajopen.ca
Background: Regional variability in antibiotic use is associated with both antibiotic overuse
and antimicrobial resistance. Our objectives were to benchmark outpatient antibiotic use and …

The Drivers of Acute and Long-term Care Clostridium difficile Infection Rates: A Retrospective Multilevel Cohort Study of 251 Facilities

KA Brown, N Daneman, M Jones… - Clinical Infectious …, 2017 - academic.oup.com
Background Drivers of differences in Clostridium difficile incidence across acute and long-term
care facilities are poorly understood. We sought to obtain a comprehensive picture of C. …

Increased environmental sample area and recovery of Clostridium difficile spores from hospital surfaces by quantitative PCR and enrichment culture

KA Brown, LK MacDougall, K Valenta… - Infection Control & …, 2018 - cambridge.org
ObjectiveClostridium difficile spores play an important role in transmission and can survive
in the environment for several months. Optimal methods for measuring environmental C. …

The mobility gap: estimating mobility levels required to control Canada's winter COVID-19 surge (preprint)

KA Brown, JPR Soucy, SA Buchan, SL Sturrock, I Berry… - 2021 - pesquisa.bvsalud.org
Background Non-pharmaceutical interventions remain a primary means of suppressing
COVID-19 until vaccination coverage is sufficient to achieve herd immunity. We used …