Objectives Data on the use of intravenous (IV) fosfomycin in Canada are limited. Using data
captured by the Canadian LEadership on Antimicrobial Real-life usage (CLEAR) registry, …

Objectives Ceftobiprole is an advanced-generation cephalosporin with a favourable safety
profile. Published data on the clinical use of ceftobiprole are limited. We report use of …

Background: Patient-level surveillance of antimicrobial use (AMU) in Canadian hospitals
empowers the reduction of inappropriate AMU and was piloted in 2017 among 14 hospitals in …

Background Antimicrobial resistance is a growing threat to the world’s ability to prevent and
treat infections. Links between quantitative antibiotic use and the emergence of bacterial …

Objectives Six months following the implementation of handshake stewardship rounds in
our intensive care unit, we performed a cross-sectional survey of critical care physicians to …

Objectives Ceftolozane/tazobactam is a cephalosporin/β-lactamase inhibitor combination with
activity against Gram-negative bacilli. Here we report the use of ceftolozane/tazobactam in …

Legionella species are Gram-negative bacilli that are relatively rare causes of community-acquired
pneumonia but can be associated with significant morbidity and mortality if …

Interrupted time series (ITS) design is a quasi-experimental approach for evaluating the
impact of an intervention in public health research using segmented linear regression (SLR) …

Background Up to 50% of antimicrobial use in hospitals has been shown to be inappropriate
and is associated with the development of antimicrobial resistance, prolonged hospital stay, …

Background Benzodiazepines and sedative-hypnotic drugs (BZD/SHDs), such as zopiclone
and the antidepressant trazodone, pose a number of risks such as falls, fractures, and …