User profiles for Jeffrey D. Whitman

Jeffrey D Whitman

University of California, San Francisco
Verified email at ucsf.edu
Cited by 1395

[HTML][HTML] Evaluation of SARS-CoV-2 serology assays reveals a range of test performance

JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu… - Nature …, 2020 - nature.com
Appropriate use and interpretation of serological tests for assessments of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and potential immunity …

[HTML][HTML] Test performance evaluation of SARS-CoV-2 serological assays

JD Whitman, J Hiatt, CT Mowery, BR Shy… - Nature …, 2020 - ncbi.nlm.nih.gov
Appropriate use and interpretation of serological tests for assessments of SARS-CoV-2
exposure, infection and potential immunity require accurate assay performance data. We …

Magnitude and kinetics of anti–severe acute respiratory syndrome coronavirus 2 antibody responses and their relationship to disease severity

KL Lynch, JD Whitman, NP Lacanienta… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can
be detected indirectly by measuring the host immune response. For some viruses, antibody …

[HTML][HTML] SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood

…, P Williamson, NK Hills, CM Lu, JD Whitman… - Nature …, 2020 - nature.com
Given the limited availability of serological testing to date, the seroprevalence of SARS-CoV-2-specific
antibodies in different populations has remained unclear. Here, we report very …

SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19

…, H Li, PY Chen, K Nakamura, JD Whitman… - Science translational …, 2021 - science.org
Although coronavirus disease 2019 (COVID-19) causes cardiac dysfunction in up to 25% of
patients, its pathogenesis remains unclear. Exposure of human induced pluripotent stem cell …

Chagas disease in the United States: a public health approach

C Bern, LA Messenger, JD Whitman… - Clinical microbiology …, 2019 - Am Soc Microbiol
Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by triatomine
vectors. An estimated 20 to 30% of infected individuals develop potentially lethal cardiac …

[HTML][HTML] Updated estimates and mapping for prevalence of Chagas disease among adults, United States

A Irish, JD Whitman, EH Clark, R Marcus… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
We combined American Community Survey data with age-specific Trypanosoma cruzi
prevalence derived from US surveys and World Health Organization reports to yield estimates of …

[HTML][HTML] SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients

…, WR Flanigan, H Li, K Nakamura, JD Whitman… - BioRxiv, 2020 - ncbi.nlm.nih.gov
Although COVID-19 causes cardiac dysfunction in up to 25% of patients, its pathogenesis
remains unclear. Exposure of human iPSC-derived heart cells to SARS-CoV-2 revealed …

Surface Proteomics Reveals CD72 as a Target for In Vitro–Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL

…, JM Rivera, M Marcoulis, KL White, JD Whitman… - Cancer discovery, 2021 - AACR
Patients with MLLr B-ALL have poor prognoses despite recent immunotherapy advances.
Here, surface proteomics identifies CD72 as being enriched on MLLr B-ALL but also widely …

Chagas disease serological test performance in US blood donor specimens

JD Whitman, CA Bulman, EL Gunderson… - Journal of clinical …, 2019 - Am Soc Microbiol
Chagas disease affects an estimated 300,000 individuals in the United States. Diagnosis in
the chronic phase requires positive results from two different IgG serological tests. Three …