Systematic reviews are difficult to keep up to date, but failure to do so leads to a decay in
review currency, accuracy, and utility. We are developing a novel approach to systematic …

New approaches to evidence synthesis, which use human effort and machine automation in
mutually reinforcing ways, can enhance the feasibility and sustainability of living systematic …

While it is important for the evidence supporting practice guidelines to be current, that is
often not the case. The advent of living systematic reviews has made the concept of “living …

Background: Although several tools to evaluate the credibility of health care guidelines exist,
guidance on practical steps for developing guidelines is lacking. We systematically …

A living systematic review (LSR) should keep the review current as new research evidence
emerges. Any meta-analyses included in the review will also need updating as new material …

Background Guidelines and quality indicators (for example as part of a quality assurance
scheme) aim to improve health care delivery and health outcomes. Ideally, the development of …

Background Although randomized clinical trials (RCTs) are considered the gold standard of
evidence, their reporting is often suboptimal. Trial registries have the potential to contribute …

Background Allergic rhinitis (AR) affects 10% to 40% of the population. It reduces quality of
life and school and work performance and is a frequent reason for office visits in general …

Background Guideline developers can: (1) adopt existing recommendations from others; (2)
adapt existing recommendations to their own context; or (3) create recommendations de …

Description: This guideline updates the 2017 American College of Physicians (ACP)
recommendations on pharmacologic treatment of primary osteoporosis or low bone mass to prevent …