Making sense of rapidly evolving evidence on genetic associations is crucial to making
genuine advances in human genomics and the eventual integration of this information in the …

A map of 191 single-nucleotide polymorphism (SNPs) was built across a 5-Mb segment
from chromosome 13q34 that has been genetically linked to schizophrenia. DNA from 213 …

Background Not all obese subjects have an adverse metabolic profile predisposing them to
developing type 2 diabetes or cardiovascular disease. The BioSHaRE-EU Healthy Obese …

Importance There are limited high-quality, population-level data about the effect of SARS-CoV-2
infection on pregnancy using contemporaneous comparator cohorts. Objectives To …

The objective of this study was to assess the relation between long-term exposure to different
aluminum (Al) forms in drinking water and Alzheimer's disease (AD). The study participants …

Ambient air pollution increases the risk of respiratory mortality, but evidence for impacts on
lung function and chronic obstructive pulmonary disease (COPD) is less well established. …

Background Despite earlier doubts, a string of recent successes indicates that if sample sizes
are large enough, it is possible—both in theory and in practice—to identify and replicate …

Background: Research in modern biomedicine and social science requires sample sizes so
large that they can often only be achieved through a pooled co-analysis of data from several …

The advent of genome-wide association studies has accelerated the discovery of novel
genetic markers, in particular single nucleotide polymorphisms (SNPs) that are associated with …

Biobanks can have a pivotal role in elucidating disease etiology, translation, and advancing
public health. However, meeting these challenges hinges on a critical shift in the way …