Cefiderocol: a siderophore cephalosporin with activity against carbapenem-resistant and multidrug-resistant gram-negative bacilli

…, S Zelenitsky, K Wiebe, CK Lawrence, HJ Adam… - Drugs, 2019 - Springer
Cefiderocol is an injectable siderophore cephalosporin discovered and being developed by
Shionogi & Co., Ltd., Japan. As with other β-lactam antibiotics, the principal antibacterial/…

Molecular epidemiology of extended-spectrum β-lactamase-, AmpC β-lactamase- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae …

…, JA Karlowsky, DJ Hoban, HJ Adam… - Journal of …, 2013 - academic.oup.com
Objectives To assess the proportion of Escherichia coli and Klebsiella pneumoniae from
Canadian hospitals that produce extended-spectrum β-lactamases (ESBLs), AmpC β-…

Antimicrobial susceptibility of 22746 pathogens from Canadian hospitals: results of the CANWARD 2007–11 study

GG Zhanel, HJ Adam, MR Baxter, J Fuller… - Journal of …, 2013 - academic.oup.com
Objectives The purpose of the CANWARD study was to assess the antimicrobial activity of a
variety of available agents against 22 746 pathogens isolated from patients in Canadian …

Identification of blood culture isolates directly from positive blood cultures by use of matrix-assisted laser desorption ionization–time of flight mass spectrometry and a …

PRS Lagacé-Wiens, HJ Adam… - Journal of clinical …, 2012 - Am Soc Microbiol
Matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry
represents a revolution in the rapid identification of bacterial and fungal pathogens in the …

Antimicrobial resistance in urinary tract pathogens in Canada from 2007 to 2009: CANWARD surveillance study

…, PJ Simner, MR DeCorby, HJ Adam… - Antimicrobial agents …, 2011 - Am Soc Microbiol
From January 2007 to December 2009, an annual Canadian national surveillance study (CANWARD)
tested 2,943 urinary culture pathogens for antimicrobial susceptibilities according …

Prevalence of antimicrobial resistance among clinical isolates of Bacteroides fragilis group in Canada in 2010-2011: CANWARD surveillance study

JA Karlowsky, AJ Walkty, HJ Adam… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Clinical isolates of the Bacteroides fragilis group (n = 387) were collected from patients
attending nine Canadian hospitals in 2010-2011 and tested for susceptibility to 10 antimicrobial …

Characterization of MDR and XDR Streptococcus pneumoniae in Canada, 2007–13

…, B Fultz, KA Nichol, HJ Adam… - Journal of …, 2015 - academic.oup.com
Objectives The goal of this study was to characterize Streptococcus pneumoniae demonstrating
MDR (resistant to three or more antimicrobial classes) or XDR (resistant to five or more …

Omadacycline: a novel oral and intravenous aminomethylcycline antibiotic agent

…, J Esquivel, S Zelenitsky, CK Lawrence, HJ Adam… - Drugs, 2020 - Springer
Omadacycline is a novel aminomethylcycline antibiotic developed as a once-daily, intravenous
and oral treatment for acute bacterial skin and skin structure infection (ABSSSI) and …

In vitro activity of eravacycline against 2213 Gram-negative and 2424 Gram-positive bacterial pathogens isolated in Canadian hospital laboratories: CANWARD …

GG Zhanel, MR Baxter, HJ Adam, J Sutcliffe… - … and infectious disease, 2018 - Elsevier
Gram-negative (n = 2213) and Gram-positive (n = 2424) pathogens isolated from patients in
13 Canadian hospitals in 2014 and 2015 were tested for in vitro susceptibility to …

Evaluation of three MALDI‐TOF mass spectrometry libraries for the identification of filamentous fungi in three clinical microbiology laboratories in Manitoba, Canada

…, KA Nichol, P Lagacé‐Wiens, P Pieroni, HJ Adam… - Mycoses, 2018 - Wiley Online Library
Matrix‐assisted laser desorption ionisation‐time of flight mass spectrometry ( MALDI ‐ TOF
MS ) is commonly used by clinical microbiology laboratories to identify bacterial pathogens …