Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly emerged
coronavirus that is responsible for the current pandemic of coronavirus disease 2019 (COVID-19), …
coronavirus that is responsible for the current pandemic of coronavirus disease 2019 (COVID-19), …
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
An ideal therapeutic anti-SARS-CoV-2 antibody would resist viral escape 1 , 2 – 3 , have
activity against diverse sarbecoviruses 4 , 5 , 6 – 7 , and be highly protective through viral …
activity against diverse sarbecoviruses 4 , 5 , 6 – 7 , and be highly protective through viral …
[PDF][PDF] Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
…, L Elzi, P Ferrari, C Garzoni, A Riva, G Snell… - Cell, 2020 - cell.com
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-CoV-2
infection is crucial for understanding immune protection and identifying targets for …
infection is crucial for understanding immune protection and identifying targets for …
Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase
…, RJ Skene, ML Kraus, DN Scheibe, GP Snell… - Journal of Biological …, 2004 - ASBMB
The activity of the c-Kit receptor protein-tyrosine kinase is tightly regulated in normal cells,
whereas deregulated c-Kit kinase activity is implicated in the pathogenesis of human cancers. …
whereas deregulated c-Kit kinase activity is implicated in the pathogenesis of human cancers. …
Broad sarbecovirus neutralization by a human monoclonal antibody
The recent emergence of SARS-CoV-2 variants of concern 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 – 10
and the recurrent spillovers of coronaviruses 11 , 12 into the human population highlight the …
and the recurrent spillovers of coronaviruses 11 , 12 into the human population highlight the …
High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875
…, J Yano, Y Hirozane, G Kefala, F Gruswitz, G Snell… - Nature, 2014 - nature.com
Human GPR40 receptor (hGPR40), also known as free fatty-acid receptor 1 (FFAR1), is a G-protein-coupled
receptor that binds long-chain free fatty acids to enhance glucose-…
receptor that binds long-chain free fatty acids to enhance glucose-…
Sensitivity of SARS-CoV-2 B. 1.1. 7 to mRNA vaccine-elicited antibodies
, … & analysis and visualization Snell Luke B. 52… - Nature, 2021 - nature.com
Transmission of SARS-CoV-2 is uncontrolled in many parts of the world; control is compounded
in some areas by the higher transmission potential of the B.1.1.7 variant 1 , which has …
in some areas by the higher transmission potential of the B.1.1.7 variant 1 , which has …
Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern evades antibody-mediated immunity that comes from vaccination or infection with …
concern evades antibody-mediated immunity that comes from vaccination or infection with …
SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern
…, C Garzoni, WC Van Voorhis, LE Rosen, G Snell… - Science, 2021 - science.org
A novel variant of concern (VOC) named CAL.20C (B.1.427/B.1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide, W152C …
detected in California, carries spike glycoprotein mutations S13I in the signal peptide, W152C …
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
