User profiles for Gregory M. Goldgof

Dr. Gregory M. Goldgof MD, PhD

Memorial Sloan Kettering Cancer Center
Verified email at mskcc.org
Cited by 2217

Finding covid-19 from chest x-rays using deep learning on a small dataset

LO Hall, R Paul, DB Goldgof, GM Goldgof - arXiv preprint arXiv …, 2020 - arxiv.org
Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative
rate is projected to be as high as 30% and test results can take some time to obtain. X-ray …

[HTML][HTML] Evaluation of SARS-CoV-2 serology assays reveals a range of test performance

…, R Yu, TN Yamamoto, U Rathore, GM Goldgof… - Nature …, 2020 - nature.com
Appropriate use and interpretation of serological tests for assessments of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and potential immunity …

[HTML][HTML] Test performance evaluation of SARS-CoV-2 serological assays

…, R Yu, TN Yamamoto, U Rathore, GM Goldgof… - Nature …, 2020 - ncbi.nlm.nih.gov
Appropriate use and interpretation of serological tests for assessments of SARS-CoV-2
exposure, infection and potential immunity require accurate assay performance data. We …

Magnitude and kinetics of anti–severe acute respiratory syndrome coronavirus 2 antibody responses and their relationship to disease severity

…, SA Kastner, BR Shy, GM Goldgof… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can
be detected indirectly by measuring the host immune response. For some viruses, antibody …

[HTML][HTML] Open source drug discovery with the malaria box compound collection for neglected diseases and beyond

…, S Gokool, B Gold, T Golub, GM Goldgof… - PLoS …, 2016 - journals.plos.org
A major cause of the paucity of new starting points for drug discovery is the lack of interaction
between academia and industry. Much of the global resource in biology is present in …

[HTML][HTML] SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood

DL Ng, GM Goldgof, BR Shy, AG Levine… - Nature …, 2020 - nature.com
Given the limited availability of serological testing to date, the seroprevalence of SARS-CoV-2-specific
antibodies in different populations has remained unclear. Here, we report very …

A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood

…, AC Granados, YA Santos, V Servellita, GM Goldgof… - Science …, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus
disease-19 (COVID-19), has emerged as the cause of a global pandemic. We used RNA …

Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity

…, CA Boyle, E Vigil, L Wang, GM Goldgof… - Journal of medicinal …, 2017 - ACS Publications
Naturally derived chemical compounds are the foundation of much of our pharmacopeia,
especially in antiproliferative and anti-infective drug classes. Here, we report that a naturally …

Direct transfer of whole genomes from bacteria to yeast

BJ Karas, J Jablanovic, L Sun, L Ma, GM Goldgof… - nature methods, 2013 - nature.com
Transfer of genomes into yeast facilitates genome engineering for genetically intractable
organisms, but this process has been hampered by the need for cumbersome isolation of intact …

Discovery of a generalization gap of convolutional neural networks on COVID-19 X-rays classification

KB Ahmed, GM Goldgof, R Paul, DB Goldgof… - Ieee …, 2021 - ieeexplore.ieee.org
A number of recent papers have shown experimental evidence that suggests it is possible
to build highly accurate deep neural network models to detect COVID-19 from chest X-ray …