New guidelines for the management of chronic kidney disease have been developed by the
Canadian Society of Nephrology (Appendix 1 contains the fulltext guidelines; available at …

Background Short-term treatment for people with type 2 diabetes using a low dose of the
selective endothelin A receptor antagonist atrasentan reduces albuminuria without causing …

OBJECTIVE: We evaluated the inter-rater reliability (IRR) of assessing the quality of evidence
(QoE) using the Grading of Recommendations, Assessment, Development, and Evaluation …

Patients undergoing conventional maintenance hemodialysis typically receive three sessions
per week, each lasting 2.5–5.5 hours. Recently, the use of more intensive hemodialysis (> …

Patients who have end-stage renal failure and are treated by hemodialysis (HD) face a stressful
chronic illness with a demanding treatment regimen that affects quality of life. Quality-of-…

Several studies have reported improved outcomes with daily hemodialysis (DHD), but the
strength of this evidence has not been evaluated. The published evidence on DHD was …

To achieve sustainable change, quality improvement initiatives must become the new way
of working rather than something added on to routine clinical care. However, most …

Quality improvement involves a combined effort among health care staff and stakeholders to
diagnose and treat problems in the health care system. However, health care professionals …

… Nesrallah, Reem A. Mustafa, William F. Clark, Adam Bass, Lianne Barnieh, Brenda R. …
Gihad Nesrallah and Louise Moist drafted and revised the manuscript. Lianne Barnieh and Adam …

Whether the duration of hemodialysis treatments improves outcomes remains controversial.
Here, we evaluated survival and clinical changes associated with converting from …