User profiles for Gerald Minuk

Gerald Minuk

Professor of medicine
Verified email at umanitoba.ca
Cited by 14905

Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with …

T Poynard, P Marcellin, SS Lee, C Niederau, GS Minuk… - The Lancet, 1998 - thelancet.com
Background Only 15–20% of patients with chronic hepatitis C achieve a sustained virological
response with interferon therapy. The aim of this study was to compare the efficacy and …

Fatty infiltration of liver in hyperlipidemic patients

…, K Kaita, D Mymin, C Levy, B Rosser, G Minuk - Digestive diseases and …, 2000 - Springer
Hyperlipidemia is a known risk factor for fatty infiltration of the liver, a condition that can
progress to cirrhosis and liver failure. The objectives of this study were to document the …

The Canadian Multicenter Double-blind Randomized Controlled Trial of ursodeoxycholic acid in primary biliary cirrhosis

…, LM Blendis, CN Ghent, P Michieletti, GY Minuk… - Hepatology, 1994 - journals.lww.com
Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal
amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile …

Treatment of Hepatitis B e Antigen–Positive Chronic Hepatitis with Telbivudine or Adefovir: A Randomized Trial

…, YM Moon, YC Chao, RP Myers, GY Minuk… - Annals of internal …, 2007 - acpjournals.org
Background: The efficacy of nucleoside and nucleotide analogues for hepatitis B has been
linked to the magnitude and durability of hepatitis B virus (HBV) suppression. Objective: To …

Occult hepatitis B virus infection in a North American adult hemodialysis patient population

GY Minuk, DF Sun, R Greenberg, M Zhang… - …, 2004 - Wiley Online Library
Hepatitis B virus (HBV) infections continue to occur in adult hemodialysis units. A possible
contributing factor is the presence of occult HBV (serum hepatitis B surface antigen [HBsAg] …

Shear stress-induced nitric oxide release triggers the liver regeneration cascade

JM Schoen, HH Wang, GY Minuk, WW Lautt - Nitric oxide, 2001 - Elsevier
The trigger of the liver regeneration cascade is currently unknown and has been the subject
of debate. We hypothesize that, following 2/3 partial hepatectomy (PHX), an increase in the …

Occult hepatitis B virus infection in a North American community-based population

GY Minuk, D Sun, J Uhanova, M Zhang, S Caouette… - Journal of …, 2005 - Elsevier
BACKGROUND/AIMS: Occult hepatitis B virus (HBV) infection [HBV-DNA detection in hepatitis
B surface antigen (HBsAg)-negative individuals] may cause acute and/or chronic liver …

[PDF][PDF] Antioxidative function of L‐FABP in L‐FABP stably transfected Chang liver cells

G Wang, Y Gong, J Anderson, D Sun, G Minuk… - …, 2005 - Wiley Online Library
Liver fatty acid binding protein (L‐FABP) contains amino acids that are known to possess
antioxidant function. In this study, we tested the hypothesis that L‐FABP may serve as an …

Clinical Hepatology: Profile of An Urban, Hospital–Based Practic

D Byron, GY Minuk - Hepatology, 1996 - journals.lww.com
To dispel the common notion that the practice of hepatology in North America largely consists
of the care of middle–aged male patients with alcohol–induced liver disease, and, in the …

Molecular evolution of hepatitis B virus over 25 years

…, E Giles, Y Tanaka, M Mizokami, GY Minuk - Journal of …, 2006 - Am Soc Microbiol
Determining the longitudinal molecular evolution of hepatitis B virus (HBV) is difficult due to
HBV's genomic complexity and the need to study paired samples collected over long periods …