Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

…, T Benard, V Beqiri, L Beretta, F Bernard… - The Lancet …, 2017 - thelancet.com
A concerted effort to tackle the global health problem posed by traumatic brain injury (TBI) is
long overdue. TBI is a public health challenge of vast, but insufficiently recognised, …

Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study

…, DC Scales, KEA Burns, L Moore, DA Zygun, F Bernard… - Cmaj, 2011 - Can Med Assoc
Background: Severe traumatic brain injury often leads to death from withdrawal of life-sustaining
therapy, although prognosis is difficult to determine. Methods: To evaluate variation in …

Brain lesions in septic shock: a magnetic resonance imaging study

T Sharshar, R Carlier, F Bernard, C Guidoux… - Intensive care …, 2007 - Springer
Background Understanding of sepsis-induced brain dysfunction remains poor, and relies
mainly on data from animals or post-mortem studies in patients. The current study provided …

Diastolic dysfunction is predictive of difficult weaning from cardiopulmonary bypass

F Bernard, A Denault, D Babin, C Goyer… - Anesthesia & …, 2001 - journals.lww.com
Diastolic function is receiving more attention since echocardiographic measurements were
developed and have become widely available. The importance and significance of diastolic …

Brain Oxygen Optimization in Severe Traumatic Brain Injury (BOOST-3): a multicentre, randomised, blinded-endpoint, comparative effectiveness study of brain tissue …

F Bernard, W Barsan, R Diaz-Arrastia, LH Merck… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Management of traumatic brain injury (TBI) includes invasive monitoring to
prevent secondary brain injuries. Intracranial pressure (ICP) monitor is the main measurement …

Rest-activity cycle disturbances in the acute phase of moderate to severe traumatic brain injury

…, DK Menon, F Bernard… - … and neural repair, 2014 - journals.sagepub.com
Background. Sleep-wake disturbances are among the most persistent sequelae after
traumatic brain injury (TBI) and probably arise during the hospital stay following TBI. These …

Magnetic resonance imaging changes in the pituitary gland following acute traumatic brain injury

…, V Newcombe, J Nortje, P Bradley, F Bernard… - Intensive care …, 2008 - Springer
Objective The objective was to study the anatomical changes in the pituitary gland following
acute moderate or severe traumatic brain injury (TBI). Design Retrospective, observational, …

Risk of delayed intracranial hemorrhage in anticoagulated patients with mild traumatic brain injury: systematic review and meta-analysis

JM Chauny, M Marquis, F Bernard, D Williamson… - The Journal of …, 2016 - Elsevier
Background Delayed intracranial hemorrhage is a potential complication of head trauma in
anticoagulated patients. Objective Our aim was to use a systematic review and meta-analysis …

[PDF][PDF] Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine.

B Frances, R Gout, B Monsarrat, J Cros… - Journal of Pharmacology …, 1992 - Citeseer
BERNARD FRANCES, ROBERT GOUT, BERNARD MONSARRAT, JEAN CROS and
JEAN-MARIE ZAJAC … content of @i(>75%) and sc(80%) sites (Frances et a!., 1985). Rat …

Age-dependent increase in hydrogen peroxide production by cardiac monoamine oxidase A in rats

A Maurel, C Hernandez, O Kunduzova… - American Journal …, 2003 - journals.physiology.org
Oxidative stress is one of the factors involved in age-related impairment of cardiac function.
In the present study, we investigated the role of the catecholamine-degrading enzyme …