Rapid pneumococcal evolution in response to clinical interventions

…, CM Parry, LM Lambertsen, D Shahinas, DR Pillai… - science, 2011 - science.org
Epidemiological studies of the naturally transformable bacterial pathogen Streptococcus
pneumoniae have previously been confounded by high rates of recombination. Sequencing …

[HTML][HTML] A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms

…, H Noedl, JB Ouédraogo, DR Pillai… - … England Journal of …, 2016 - Mass Medical Soc
Background Recent gains in reducing the global burden of malaria are threatened by the
emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations …

[HTML][HTML] Ceftiofur resistance in Salmonella enterica serovar Heidelberg from chicken meat and humans, Canada

L Dutil, R Irwin, R Finley, LK Ng, B Avery… - Emerging infectious …, 2010 - ncbi.nlm.nih.gov
The Canadian Integrated Program for Antimicrobial Resistance Surveillance describes a
strong correlation (r= 0.9, p< 0.0001) between ceftiofur-resistant Salmonella enterica serovar …

Success of self-administered home fecal transplantation for chronic Clostridium difficile infection

MS Silverman, I Davis, DR Pillai - Clinical Gastroenterology and …, 2010 - Elsevier
BACKGROUND & AIMS: Clostridium difficile infection (CDI) can relapse in patients with
significant comorbidities. A subset of these patients becomes dependent on oral vancomycin …

Practical guidance for clinical microbiology laboratories: laboratory diagnosis of parasites from the gastrointestinal tract

…, E Kokoskin, GP Paltridge, DR Pillai… - Clinical microbiology …, 2018 - Am Soc Microbiol
This Practical Guidance for Clinical Microbiology document on the laboratory diagnosis of
parasites from the gastrointestinal tract provides practical information for the recovery and …

[HTML][HTML] A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America

…, A Scheinerman, N Roubinian, G Yu, E Kim, DR Pillai… - PloS one, 2010 - journals.plos.org
Although metagenomics has been previously employed for pathogen discovery, its cost and
complexity have prevented its use as a practical front-line diagnostic for unknown infectious …

Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing

…, E Allen-Vercoe, S Weese, A Wong, DE Low, DR Pillai - MBio, 2012 - Am Soc Microbiol
Fecal microbiome transplantation by low-volume enema is an effective, safe, and inexpensive
alternative to antibiotic therapy for patients with chronic relapsing Clostridium difficile …

[HTML][HTML] A multicenter study investigating SARS-CoV-2 in tertiary-care hospital wastewater. viral burden correlates with increasing hospitalized cases as well as …

…, J Hu, JL Cabaj, NJ Ruecker, C Naugler, DR Pillai… - Water Research, 2021 - Elsevier
SARS-CoV-2 has been detected in wastewater and its abundance correlated with
community COVID-19 cases, hospitalizations and deaths. We sought to use wastewater-based …

[HTML][HTML] Mutations in Plasmodium falciparum K13 propeller gene from Bangladesh (2009–2013)

…, AG Bayih, A Folefoc, D Shahinas, R Haque, DR Pillai - Malaria journal, 2014 - Springer
Background Bangladesh is a malaria hypo-endemic country sharing borders with India and
Myanmar. Artemisinin combination therapy (ACT) remains successful in Bangladesh. An …

[HTML][HTML] Genome-wide dissection of globally emergent multi-drug resistant serotype 19A Streptococcus pneumoniae

DR Pillai, D Shahinas, A Buzina, RA Pollock, R Lau… - BMC genomics, 2009 - Springer
Background Emergence of multi-drug resistant (MDR) serotype 19A Streptococcus pneumoniae
(SPN) is well-documented but causal factors remain unclear. Canadian SPN isolates (…