Background Chemotherapy plus radiation treatment is effective in controlling stage IA or IIA
nonbulky Hodgkin's lymphoma in 90% of patients but is associated with late treatment-…

Background The efficacy of autologous stem-cell transplantation during the first remission in
patients with diffuse, aggressive non-Hodgkin's lymphoma classified as high-intermediate …

Although the combination of lenalidomide and dexamethasone is effective therapy for
patients with relapsed/refractory multiple myeloma, the influence of high-risk cytogenetic …

Background aims Anti-thymocyte globulin (ATG) is being used increasingly to prevent graft-versus-host
disease (GvHD); however, its impact on immune reconstitution is relatively …

Integrin-β7 (ITGB7) mRNA is detected in multiple myeloma (MM) cells and its presence is
correlated with MAF gene activation. Although the involvement of several integrin family …

Chromosomal instability is a defining feature of clonal myeloma plasma cells that results in
the perpetual accumulation of genomic aberrations. In addition to its role in protein …

Goals of the work The goal of this study was to examine the association between exercise
and quality of life (QOL) in multiple myeloma cancer survivors. Patients and methods Using a …

This phase 1 study evaluated the safety, tolerability, pharmacokinetics, and antitumor activity
of obinutuzumab (GA101), a glycoengineered type II anti-CD20 monoclonal antibody …

… Stewart, Tom Baker Cancer Centre, Calgary; Neil Chua, Cross Cancer Institute,
Edmonton, Alberta; David A. MacDonald and Mohsen Alzahrani, Queen Elizabeth II Health …

Phase I pharmacokinetics (PK) and pharmacodynamics (PD) studies in healthy volunteers
demonstrated that plerixafor (AMD3100), a CXCR4 antagonist, administered either alone or …