The anti-proliferative effect of metformin in triple-negative MDA-MB-231 breast cancer cells is highly dependent on glucose concentration: implications for cancer …

BNM Zordoky, D Bark, CL Soltys, MM Sung… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Metformin has been shown to have a strong anti-proliferative effect in many
breast cancer cell lines, mainly due to the activation of the energy sensing kinase, AMP-…

SARS-CoV-2 transmission in kindergarten to grade 12 schools in the Vancouver Coastal Health region: a descriptive epidemiologic study

D Bark, N Dhillon, M St-Jean, B Kinniburgh… - … Open Access Journal, 2021 - cmajopen.ca
Background: There is an urgent need to assess the role of schools in the spread of SARS-CoV-2
in Canada to inform public health measures. We describe the epidemiology of SARS-…

Normoglycemia sensitizes MDA‐MB‐231 breast cancer cells to metformin through an AMPK‐dependent mechanism (LB610)

B Zordoky, D Bark, C Soltys, M Sung… - The FASEB …, 2014 - Wiley Online Library
Background: Metformin has been shown to have strong anti‐proliferative effect in many
breast cancer cell lines, mainly due to the activation of the energy sensing kinase, AMP‐…

SARS-CoV-2 transmission in K-12 schools in the Vancouver Coastal Health Region: a descriptive epidemiologic study (preprint)

D Bark, N Dhillon, M St-Jean, B Kinniburgh, G McKee… - 2021 - pesquisa.bvsalud.org
Background: There is an urgent need to assess the role of schools in the spread of SARS-CoV-2
in Canada to inform public health measures. We describe the epidemiology of SARS-…

An ethnobotanical survey of medicinal plants used by traditional health practitioners to manage HIV and its related opportunistic infections in Mpoza, Eastern Cape …

…, A Oluwaseyi, D Denver, M Oluchi, G Diana - Journal of …, 2015 - Elsevier
… From this study, the use of the roots and barks of these plants was approximately 26%, and
potentially in future may pose a challenge to conservation of these medicinal plants for the …

Bark beetle-fungus symbioses

DL Six - Insect symbiosis, 2003 - books.google.com
… of bark beetles, and … of bark beetle–fungal associations has been limited by a tendency to
disregard the vastly more numerous and ecologically diverse nonaggressive species of bark

[PDF][PDF] Antihyperglycemic Activity of The Ethanolic Extract of the Bark of Mitragyna Ciliata (MYCA) in Albino Induced Diabetic Rats

PP Diana, J McClain - 2021 - academia.edu
Background: Diabetes an epidemic that gives rise to an increased macro vascular
complication mortality rate of 1.5 million annually, increasing by 2035. Treatment of diabetes is …

[HTML][HTML] Ecological and evolutionary determinants of bark beetle—fungus symbioses

DL Six - Insects, 2012 - mdpi.com
… In contrast, bark beetles construct their galleries in the phloem layer of trees just under
the outer bark (Figure 3). Unlike ambrosia beetles, bark beetles feed on tree tissues (phloem), …

The bark beetle holobiont: why microbes matter

DL Six - Journal of chemical ecology, 2013 - Springer
… Finally, I discuss why it will be critical to study bark beetles as a holobiont to understand the
… I then turn to describing the state of knowledge of the bark beetle holobiont. Bark beetles are …

A major symbiont shift supports a major niche shift in a clade of tree‐killing bark beetles

DL Six - Ecological Entomology, 2020 - Wiley Online Library
… However, members of one small clade of bark beetles within the genus Dendroctonus have
shifted from using phloem to partly or completely using outer bark (fig. 1) (Six and Bracewell, …