Our understanding of the role of T cells in human disease is undergoing revision as a result
of the discovery of T‐helper 17 (Th17) cells, a unique CD4 + T‐cell subset characterized by …

Twenty-eight patients with refractory rheumatoid arthritis completed a randomized 24-week
double-blind crossover trial comparing oral methotrexate (2.5 to 5 mg every 12 hours for …

The early events leading to the development of rheumatoid arthritis (RA) remain unclear,
but formation of autoantibodies to citrullinated protein antigens (ACPAs) is considered a key …

The evolution of grasses using C 4 photosynthesis and their sudden rise to ecological
dominance 3 to 8 million years ago is among the most dramatic examples of biome assembly in …

The evolution of research in luminescent signalling at Queen's University of Belfast is critically
reviewed in the context of related work from the literature. Photoinduced electron transfer (…

Seasonal development of dissolved-oxygen deficits (hypoxia) represents an acute system-level
perturbation to ecological dynamics and fishery sustainability in coastal ecosystems …

Computational aspects of a geometrically exact stress resultant model presented in Part I of
this work are considered in detail. In particular, by exploiting the underlying geometric …

Triangulene, the smallest triplet-ground-state polybenzenoid (also known as Clar's
hydrocarbon), has been an enigmatic molecule ever since its existence was first hypothesized 1 . …

Introduction Rheumatoid arthritis (RA) is a complex and clinically heterogeneous autoimmune
disease. Currently, the relationship between pathogenic molecular drivers of disease in …

The heart is not only our most vital, but also our most complex organ: Precisely controlled by
the interplay of electrical and mechanical fields, it consists of four chambers and four valves, …