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Supplement . Background: The magnitude, consistency, and manner of association between …

In the last decade, the prevalence of obesity has increased significantly in populations
worldwide. A less dramatic, but equally important increase has been seen in our knowledge of its …

Context Less than 5% of US adults accumulate the required dose of exercise to maintain
health. Behavioral economics has stimulated renewed interest in economic-based, population-…

ContextThe extent to which drug adherence may affect survival remains unclear, in part because
mortality differences may be attributable to “healthy adherer” behavioral attributes more …

ContextComparisons of outcomes between patients treated and untreated in observational
studies may be biased due to differences in patient prognosis between groups, often …

SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide
pandemic, and there is a pressing need to understand the development, specificity, and …

Background Universal health care systems seek to ensure access to care on the basis of
need rather than income and to improve the health status of all citizens. We examined the …

ContextThe benefits of cardiovascular therapies such as statins for secondary prevention have
been well documented, although they may not be optimally used in patients most likely to …

ContextThiazolidinediones (TZDs), used to treat type 2 diabetes, are associated with an
excess risk of congestive heart failure and possibly acute myocardial infarction. However, the …

Background : The prognostic importance of high-density lipoprotein cholesterol (HDL-C) as
a specific risk factor for cardiovascular (CV) disease has been challenged by recent clinical …