OBJECTIVE: This study was conducted to develop evidence‐based clinical practice
guidelines for nutrition support (ie, enteral and parenteral nutrition) in mechanically ventilated …

Background: Hyperglycemia is associated with increased mortality in critically ill patients.
Randomized trials of intensive insulin therapy have reported inconsistent effects on mortality …

ContextSeveral nutrients have been shown to influence immunologic and inflammatory
responses in humans. Whether these effects translate into an improvement in clinical outcomes …

Context Despite increasing interest in advance care planning (ACP) and previous ACP
descriptions, a consensus definition does not yet exist to guide clinical, research, and policy …

To evaluate the attributable morbidity and mortality of ventilator-associated pneumonia (VAP)
in intensive care unit (ICU) patients, we conducted a prospective, matched cohort study. …

Purpose The objective of this study was to examine the relationship between the amount of
energy and protein administered and clinical outcomes, and the extent to which pre-morbid …

Advance care planning (ACP) is increasingly implemented in oncology and beyond, but a
definition of ACP and recommendations concerning its use are lacking. We used a formal …

… Address requests for reprints to: Daren K. Heyland, MD, Angada 3, Kingston General
Hospital, 76 Stuart Street, Kingston, Ontario K7L 2V7, Canada. E-mail: [email protected] …

Background Critically ill patients have considerable oxidative stress. Glutamine and antioxidant
supplementation may offer therapeutic benefit, although current data are conflicting. …

Introduction To develop a scoring method for quantifying nutrition risk in the intensive care
unit (ICU). Methods A prospective, observational study of patients expected to stay > 24 hours. …