Cardiovascular disease (CVD) is the leading cause of mortality in women. In fact, CVD is
responsible for a third of all deaths of women worldwide and half of all deaths of women over …

Background— Antiplatelet therapy is often discontinued in patients with drug-eluting stents
who are undergoing surgical procedures. However, discontinuation of antiplatelet therapy is …

Background— Coronary artery disease is a significant risk factor for atrial fibrillation (AF), but
the basis for this association is incompletely understood. The present study evaluated the …

The binding of leukocyte P-selectin glycoprotein ligand-1 (PSGL-1) to platelet P-selectin is
central to post-angioplasty restenosis. Although intracoronary stents limit the mechanical …

Objective: Heparin (HEP) is used in the post-thrombolytic state to prevent vessel reocclusion,
thereby aiding myocardial salvage. Side effects limit its benefits, but besides anticoagulant …

P-selectin is rapidly translocated from platelet α-granules following activation. Intracellular
cyclic AMP (cAMP) is a potent inhibitory pathway that results in global downregulation of …

Residual coronary stenosis is common after successful thrombolysis for acute infarction. We
investigated the role of platelets and the influence of a residual critical stenosis during early …

P-selectin is translocated from the α-granules to the surface of activated platelets where it
participates in thrombosis and inflammation. We investigated the signaling pathways involved …

Platelet-related events being associated with the increment of infarct size at reperfusion in
the presence of a residual stenosis, we tested in dogs whether intravenous aspirin (ASA) …

Background—Antiplatelet therapy is often discontinued in patients with drug-eluting stents
who are undergoing surgical procedures. However, discontinuation of antiplatelet therapy is …