We reviewed current guidelines on the management of polycythemia vera. For questions
regarding the diagnostic investigation of erythrocytosis and the utility of specific laboratory tests …

Background: Patients with essential thrombocythemia (ET) are at high risk for both thrombosis
and hemorrhage. Purpose: To evaluate the risks and benefits of antithrombotic therapy in …

The acute phase of venous thromboembolism (VTE) treatment focuses on the prompt and
safe initiation of full-dose anticoagulation to decrease morbidity and mortality. Immediate …

Background: Intensive care unit (ICU) patients are at high risk of anemia, which is associated
with adverse clinical outcomes and death. Blood sampling for diagnostic testing is a …

Choosing Wisely Canada (CWC), a medical stewardship campaign, encourages dialogue
between physicians and patients to promote high-quality decision-making. Medical societies …

An acute transfusion reaction (ATR) is any reaction to blood, blood components, or plasma
derivatives that occurs within 24 hours of a transfusion. The frequencies of ATRs and the …

Background With increasing global use of intravenous immunoglobulin (IVIG), there is interest
in its appropriate usage. Efforts to regulate IVIG usage have primarily taken the form of …

Therapy in Polycythemia Vera (PV), a myeloproliferative neoplasm, focuses on reducing
cardiovascular (CV) risk without increasing bleeding or hematological progression. However, …

The patient’s CHA2DS2-VASc score is 4. This risk score attempts to improve the estimation
of stroke risk, particularly at lower CHADS2 scores, by considering additional risk factors …

INTRODUCTION Patients with myelodysplastic syndrome (MDS) frequently receive red blood
cell (RBC) transfusions to alleviate symptoms of fatigue and improve well-being, yet their …