Background Government interventions are critical to addressing the global tobacco epidemic,
a major public health problem that continues to deepen. We systematically synthesize …

Background Celebrities can have substantial influence as medical advisors. However, their
impact on public health is equivocal: depending on the advice’s validity and applicability, …

Objective To synthesise what is known about how celebrities influence people’s decisions
on health. Design Meta-narrative analysis of economics, marketing, psychology, and …

Objective to examine the diagnostic accuracy of traditional ‘red flags’ for necrotizing fasciitis
(NF) on history and physical examination. Methods retrospective study of all cases of NF …

Background Infective endocarditis is associated with high morbidity and mortality rates that
have plateaued over recent decades. Research to improve outcomes for these patients is …

Importance People who inject drugs (PWID) who are being treated for infective endocarditis
remain at risk of new bloodstream infections (BSIs) due to ongoing intravenous drug use (…

Background The rising incidence of infective endocarditis (IE) among people who inject
drugs (PWID) has been a major concern across North America. The coincident rise in IE and …

Objective:Extracorporeal membrane oxygenation (ECMO) has been widely used in the care
of patients with respiratory failure from coronavirus disease 2019 (COVID-19). We …

OBJECTIVEThe relationship between hospital antibiotic use and antibiotic resistance is poorly
understood. We evaluated the association between antibiotic utilization and resistance in …

Introduction Treatment of opioid addiction with methadone is effective; however, it is known
to produce interindividual variability. This may be influenced in part by genetic variants, …