Background Persistent organ failure and infected pancreatic necrosis are major determinants
of mortality in acute pancreatitis, but there is a gap in the literature assessing the best …

Cardiac dysfunction resulting from sepsis may cause significant morbidity and mortality, and
ferroptosis plays a role in this pathology. Dexmedetomidine (Dex), a α2‑adrenergic receptor …

Nonintegrating lentiviral (NIL) vectors were produced from HIV-1-based lentiviral vectors by
introducing combinations of mutations made to disable the integrase protein itself and to …

Background Implementation science studies often express interest in “attitudes,” a term
borrowed from psychology. In psychology, attitude research has an established methodological …

DNA-bound transcription factors recruit many coactivator proteins to remodel chromatin and
activate transcription. The Mediator complex is believed to recruit RNA polymerase II to most …

Cancer is still one of the leading causes of death in the world. There are over 200 types of
cancers currently known according to the National Cancer Institute. However, early diagnosis …

The biosynthetic gene cluster for the enediyne antitumor antibiotic neocarzinostatin (NCS)
was localized to 130 kb continuous DNA from Streptomyces carzinostaticus ATCC15944 and …

Amplified inflammatory reaction has been observed to be involved in cardiometabolic
diseases such as obesity, insulin resistance, diabetes, dyslipidemia, and atherosclerosis. The …

BACKGROUND: Readmission rates are a measure of surgical quality and an object of clinical
and regulatory scrutiny. Despite increasing efforts to improve quality and contain cost, 6% …

Background Surgical intervention has traditionally been reserved as the last management
option for pain in chronic pancreatitis. Recently, there has been a call for surgery to be offered …